Week 2: Pain Flashcards

1
Q

What is pain

A

-unpleasant sensation
-discomfort caused by stim.of pain receptors

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2
Q

what causes pain

A

-Inflammation
- Infection
- Ischemia and tissue necrosis
- Stretching of tissue
- Stretching of tendons, ligaments, joint capsule
- Chemicals
- Burns
- Muscle spasm

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3
Q

what is somatic pain

A

from the skin (cutaneous)
bone muscle
conducted by sensory fibres

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4
Q

what is visceral pain

A

originates in organs
conducted by sympathetic fibres
may be acute or chronic

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5
Q

what are sensory dimensions

A

the perception of pain by the individ

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6
Q

what do sensory dimensions include

A

location
intensity
pattern
quality

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7
Q

pain threshold

A

point at which stimulus is perceived as pain

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8
Q

whats a pain tolerance

A

max intensity or duration of pain that a person can endure before acting

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9
Q

whats an autonomic pain response

A

protecting an individual

ex. moving hand from a hot stove

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10
Q

whats a behavioural pain resposne

A

learned behav as a method to coping with the pain

ex. rubbing a sore leg

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11
Q

what is hyperalgesia

A

-increased sensit to pain
-result of damage to nociceptors or peripheral nerves

ex. shingles

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12
Q

what are the 4 major processes of nociception

A

transduction
transmission
perception
modulation

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13
Q

what is transduction

A

conversion of a
- mechical
- thermal
- chemical stimulus
- neuronal ap

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14
Q

mechanical stimulus

A

trauma
surgery
muscle spasm

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15
Q

thermal stimulus

A

extreme heat or cold

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16
Q

chemical stimulus

A

lactic acid
bradykinins
enzymes

17
Q

where does tranduction occur

A

free nerve endings of nociceptors

18
Q

what occurs once free nerve endings are stimulated (transduction)

A

noxious stimuli results in release of chemicals around peripheral afferent nociceptor

19
Q

what chemicals are released once free nerve endings are stimulated

A

bradykinin
serotonin
histamine
acetylcholine
substance p

20
Q

what occurs when a stimulus causes released chemicals to excite the peripheral afferent nociceptor

21
Q

what is an ap necessary for

A

convert pain stimulus to an impulse and move it from the periphery to the spinal cord

22
Q

what is transmission

A

movement of pain impulses from the site of the transduction to the brain

23
Q

what are 2 main types of peripheral nerve fibres

A

a fibers (beta and delta)
c fibers

24
Q

A fibers

A

small
myelinated
transmit signals fast
produce sharp localized pain

25
C fibers
large unmyelinated transmit signals slowly produce dull achy pain in deeper structures
26
what does dorsal horn processing include
release of nt (substance p) which may either excite or inhibit the cell
27
what happens when the pain reaches the somatosensory area in the cerebral cortex
perception and localization of sensation
28
what happens when pain reaches the hypothalamus and limbic system
emotional factors
29
what occurs within the reticular activating system
reticular formation in the pons and medulla awareness of incoming brain stimuli
30
what do cortical structures provide
meaning of pain
31
what is the perception of pain
occurs wehn pains recognized concious awareness of pain subjective interpretation
32
what are effective non medical pain reducing interventions
music distraction relaxation imagery
33
what are pathways that integrate nervous system impulses
modulation
34
what does modulation involve
activation of descending pathways that exert inhibitory or excitatory effects on pain transmission that will suppress or facilitate pain
35
where does modulation occur
periphery spinal cord brain stem cerebral cortex
36
what may be released that inhibits pain transmission
serotonin NE endogenous opiods