Week 1: Fluids & Fluid movement Flashcards
What is the major component of the body
water
what is water essential for
homeostasis
what is water a place for
metabolic rxns
what does water do for the body
transportation system
facilitates movements of body parts
whats ICF
intracellular compartment fluid inside cells
whats ECF
extracellular compartment
- intravascular IVF (vessels, veins, part of blood)
- Interstitial ISF (in cells)
- Cerebrospinal fluid (CSF in nervous system)
- Transcellular Fluids (secretions sweat, nasal, gastric)
What is the general rule for water movement
amt water entering body should equal water leaving
fluid intake
ingestion of solid food or fluids
fluid loss
urine
feces
perspiration
exhaled air
what forces control water and solute movement
hydrostatic pressure
osmotic pressure
what are the processes of water and solutes movement through a semi permeable membrane
filtration
diffusion
osmosis
active transport
filtration
in capillary arteriole
movement of water and solutes from blood
(high pressure) to ISF (low pressure)
diffusion
movement of solutes (Na+/glucose) from high to low conc at capillary level
osmosis
movement of h2o from low solute conc to high conc at venule side (ISF to blood)
active transport
movement of solute using carrier and atp from low to high conc (ISF to cell)
thirst
controlled by osmoreceptors in hypothalamus
ADH antidiuretic hormone
reabsorption of water from kidney tubules
occurs at loop henle
ANP atrial natriuretic peptide and T- type natriuretic peptide
synthesized by myocardial cells
regulation of fluid, sodium, K+`
Aldosterone
reabsorption of sodium and water
occurs at dct
Edema
excessive amount of fluid lodged in ISF compartment
- causes swelling/ enlargement of tissue
- localized or throughout body
- can impair tissue perfusion prevent blood flow
- trap drugs in ISF seeps in
what causes edema
increased capillary hydrostatic pressure
loss plasma proteins
obstruction of lymphatic circulation
increased capillary permeability
what causes capillary hydrostatic pressure
higher bp or increased blood volume
forces increased fluid out of capillaries into tissue
causes pulmonary edema
what causes loss of plasma protein
loss of albumin in kidney
decreased plasma osmotic pressure
what does obstructed lymphatic circulation cause
localized edema
excessive fluid and protein not returned to circulation