Week 15: Cannabinoids Flashcards

1
Q

The main ROA for dronabinol is

A. I.M. 
B. Oral 
C. Inhalation 
D. Topical
A

oral

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2
Q

The route of administration of Sativex is

A. Oral 
B. Oral mucosal spray
C. Inhalation 
D. Injection
A

Oral mucosal spray

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3
Q

The most ubiquitous receptors in the brain appear to be those responsive to

A. GABA
B.  Cannabinoids
C. Glutamate 
D. NMDA
A

Cannabinoids

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4
Q

Marinol is a

A. Synthetic cannabinoid agonist
B. non-synthetic cannabinoid antagonist
C. non-synthetic cannabinoid agonist
D. synthetic cannabinoid antagonist

A

Synthetic cannabinoid agonist

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5
Q

Nabiximols is a

A. Non-synthetic cannabinoid agonist
B. Synthetic cannabinoid agonist 
C. Non-synthetic cannabinoid antagonist 
D. Synthetic cannabinoid antagonist
A

Non-synthetic cannabinoid agonist

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6
Q

In California marijuana was legalized for non-medical use in

A. 1996 
B. 2016 
C. 2006 
D. It is still not legal for non-medical use
A

2016

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7
Q

Which of the following is NOT an off-label use for Epidiolex?

A. Weight loss 
B. Pain relief 
C. Management of autism symptoms 
D. Anxiety
A

weight loss

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8
Q

In the US marijuana is currently listed under which DEA schedule?

A

Schedule I

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9
Q

Hashish and marijuana differ mainly in their

A

Potency

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10
Q

A primary indication for cannabidiol is

A. Seizure reduction 
B. Depression 
C. Antipyresis 
D. ADHD
A

Seizure reduction

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11
Q

In the US _______ states have legalized marijuana for either medical or recreational use.

A. 46
B. 48
C. 42
D. 44

A

46

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12
Q

THC can take up to 5 weeks to be completely excreted from the body because

A. It is eliminated in 4 phases 
B. It is highly lipid soluble 
C. It is metabolized in neurons 
D. It has very low protein binding
A

It is highly lipid soluble

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13
Q

Which of the following is NOT a primary indication of dronabinol?

A. Nausea/vomiting 
B. Anorexia 
C. Anxiety
D. Appetite stimulation
A

anxiety

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14
Q

The major psychoactive ingredient in the marijuana plant is

A. Dronabinol 
B. Delta-9-tetrahydrocannabinol (THC) 
C. Cannabidiol 
D. Anandamide
A

Delta-9-tetrahydrocannabinol (THC)

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15
Q

epidiolex is a ______ at CB receptors

A. agonist
B. antagonist
C. inverse agonist
D. partial agonist

A

partial agonist

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16
Q

___ are lipid-soluble and are concentrated in fat

A

cannabinoids

17
Q

___ is possibly the most populous receptor in the brain

A

CB1

18
Q

2-5 mg/mL of cannabis in plasma is associated with increased risk of ___

A

auto accidents

19
Q

What is a common symptom of withdrawal from cannabis?

A

irritability

20
Q

TRUE/FALSE? There is no known toxicity of cannabis in humans

A

TRUE

21
Q

The primary indication of rimonabant is ___

A

marijuana dependence and txt for obese patients.

22
Q

___ is an inverse agonist for cannabinoid receptor CB-1

A

rimonabant