Week 15: Cannabinoids Flashcards
The main ROA for dronabinol is
A. I.M. B. Oral C. Inhalation D. Topical
oral
The route of administration of Sativex is
A. Oral B. Oral mucosal spray C. Inhalation D. Injection
Oral mucosal spray
The most ubiquitous receptors in the brain appear to be those responsive to
A. GABA B. Cannabinoids C. Glutamate D. NMDA
Cannabinoids
Marinol is a
A. Synthetic cannabinoid agonist
B. non-synthetic cannabinoid antagonist
C. non-synthetic cannabinoid agonist
D. synthetic cannabinoid antagonist
Synthetic cannabinoid agonist
Nabiximols is a
A. Non-synthetic cannabinoid agonist B. Synthetic cannabinoid agonist C. Non-synthetic cannabinoid antagonist D. Synthetic cannabinoid antagonist
Non-synthetic cannabinoid agonist
In California marijuana was legalized for non-medical use in
A. 1996 B. 2016 C. 2006 D. It is still not legal for non-medical use
2016
Which of the following is NOT an off-label use for Epidiolex?
A. Weight loss B. Pain relief C. Management of autism symptoms D. Anxiety
weight loss
In the US marijuana is currently listed under which DEA schedule?
Schedule I
Hashish and marijuana differ mainly in their
Potency
A primary indication for cannabidiol is
A. Seizure reduction B. Depression C. Antipyresis D. ADHD
Seizure reduction
In the US _______ states have legalized marijuana for either medical or recreational use.
A. 46
B. 48
C. 42
D. 44
46
THC can take up to 5 weeks to be completely excreted from the body because
A. It is eliminated in 4 phases B. It is highly lipid soluble C. It is metabolized in neurons D. It has very low protein binding
It is highly lipid soluble
Which of the following is NOT a primary indication of dronabinol?
A. Nausea/vomiting B. Anorexia C. Anxiety D. Appetite stimulation
anxiety
The major psychoactive ingredient in the marijuana plant is
A. Dronabinol B. Delta-9-tetrahydrocannabinol (THC) C. Cannabidiol D. Anandamide
Delta-9-tetrahydrocannabinol (THC)
epidiolex is a ______ at CB receptors
A. agonist
B. antagonist
C. inverse agonist
D. partial agonist
partial agonist
___ are lipid-soluble and are concentrated in fat
cannabinoids
___ is possibly the most populous receptor in the brain
CB1
2-5 mg/mL of cannabis in plasma is associated with increased risk of ___
auto accidents
What is a common symptom of withdrawal from cannabis?
irritability
TRUE/FALSE? There is no known toxicity of cannabis in humans
TRUE
The primary indication of rimonabant is ___
marijuana dependence and txt for obese patients.
___ is an inverse agonist for cannabinoid receptor CB-1
rimonabant