Week 13: Stimulants

Question 1

Which of the following is NOT a serious side effect of methamphetamine use?

A. Cardiac arrest 
B. Rhabdomyolysis 
C. Liver failure 
D. Hyperthermia

Answer 1

Liver failure

Question 2

Compared to modafinil, methylphenidate is _______ effective for the treatment of ADHD, and ________ effective for the treatment of narcolepsy

A. More; equally 
B. Equally; more
C. Equally; equally 
D. More; more

Answer 2

Equally; more

Question 3

The major pharmacodynamic mechanism of amphetamine is

Answer 3

Increased release of neurotransmitters

Question 4

Methamphetamine is made from amphetamine by substituting a ________ group.

-CH3 (methyl)
-H2
-OH
-NH3

Answer 4

CH3 (methyl)

Question 5

The primary indication of sibutramine is the treatment of

A. ADHD 
B. Obesity 
C. Sexual dysfunction 
D. Narcolepsy

Answer 5

Obesity

Question 6

Withdrawal symptoms of amphetamine dependency include all of the following EXCEPT:

-Altered pain threshold
-increased sleep
-decreased energy
-increased appetite.

Answer 6

Altered pain threshold

Question 7

Formication is defined as:

A. Feeling of insects crawling under skin
B. Compulsive, stereotyped behavior 
C. Extreme irritability 
D. Hyperaggressive behavior

Answer 7

Feeling of insects crawling under skin

Question 8

An important target area in the brain for the therapeutic effects of methylphenidate is the

-Prefrontal cortex
-nucleus accumbens
-limbic system
-basal ganglia

Answer 8

Prefrontal cortex

Question 9

Methylphenidate blocks the reuptake of

A. DA and 5-HT 
B. DA and NE 
C. DA, NE, and 5-HT 
D. DA

Answer 9

DA and NE

Question 10

Methamphetamine produces anorexigenic effects by

-Increasing CART production in the hypothalamus
-increasing sympathetic NS activation
-increasing satiety signals in the nucleus accumbens
-increasing body temperature.

Answer 10

Increasing CART production in the hypothalamus

Question 11

A drug that has the same effect as adrenaline is known as a

Answer 11

Sympathomimetic

Question 12

The therapeutic use(s) of amphetamine is/are:

Answer 12

Treatment of both narcolepsy and ADHD

Question 13

The peripheral side effects of psychostimulants resemble activation of the

A. Enteric nervous system 
B. Sympathetic nervous system
C. Parasympathetic nervous system 
D. Skeletal nervous system

Answer 13

Sympathetic nervous system

Question 14

The excretion rate of methamphetamine is dependent upon

A. Urine pH
B. Length of usage 
C. Availability of CYP2D6 in the liver 
D. ROA

Answer 14

Urine pH

Question 15

Cocaine is used medically

A. To induce amnesia 
B. To lower blood pressure 
C. To treat myocardial infarction 
D. As an anesthetic

Answer 15

As an anesthetic

Question 16

Which of the following is a short-term effect of using cocaine?

A. Dilated pupils 
B. Tooth decay 
C. Weight loss 
D. Lung damage

Answer 16

Dilated pupils

Question 17

Withdrawal symptoms of amphetamine dependency include all of the following EXCEPT

A. Decreased energy 
B. Increased appetite 
C. Altered pain threshold 
D. Increased sleep

Answer 17

Altered pain threshold

Question 18

Who is most likely at risk of death after consuming cocaine?

a young adult in her 30s
an older adult in his 70s
an adult in his 50s
an adolescent

Answer 18

an older adult in his 70s

Question 19

Stimulants are considered sympathomimetic, meaning that they ___

Answer 19

mimic the effects of adrenaline

Question 20

What is formication?

Answer 20

the feeling of insects crawling on one’s body or under one’s skin

Question 21

What is the primary indication of meridia?

Answer 21

obesity

Question 22

what is the primary indication of provigil?

Answer 22

Narcolepsy, shift-
work sleep disorder, sleep apnea