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Psychopharm Final > Quiz 10: Pain Medications > Flashcards

Quiz 10: Pain Medications Flashcards

1
Q

Ibuprofen is an especially good choice for

A. Nursing mothers
B. patients on blood-thinning meds
C. patients with peptic ulcers
D. patients with renal failure

A

Nursing mothers

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2
Q

Compared to morphine, heroin is

A

More lipid soluble

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3
Q

Suboxone is the combination of buprenorphine and

A. Naltrexone 
B. Sibutramine 
C. Naloxone 
D. Acetaminophen
A

Naloxone

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4
Q

Which of the following nuclei is NOT a part of the descending pain modification system?

A

Nucleus basalts

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5
Q

To which receptor does oxycodone bind the most?

A. GABA
B. Delta opioid 
C. Mu opioid 
D. Histamine
A

Mu opioid

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6
Q

Acetaminophen is not recommended for people who have

A. Rheumatoid arthritis
B. fever
C. chronic pain
D. acute pain

A

Rheumatoid arthritis

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7
Q

What is the pharmacodynamic action of aspirin?

A. Selective COX-1 inhibitor
B. Selective COX-2 inhibitor
C. Selective COX-1 agonist
D. Non-selective COX inhibitor

A

Non-selective COX inhibitor

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8
Q

The cell bodies of nociceptors are found in the

A. dorsal root ganglion of the spinal cord
B. the ventral root ganglion of the spinal cord
C. dorsal horns of the spinal cord
D. the ventral horns of the spinal cord.

A

Dorsal root ganglion of the spinal cord

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9
Q

In addition to stimulating mu opioid receptors, tapentadol also

A. Blocks the NET
B. stimulates DA response
C. blocks the SERT
D. stimulates 5-HT receptors

A

Blocks the NET

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10
Q

What is the primary indication for acetaminophen?

A. Depression 
B. Analgesia and antipyresis 
C. GAD and OCD
D. Bipolar disorder
A

Analgesia and antipyresis

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11
Q

Which of the following drugs is a good choice for “poor metabolizers” or patients with compromised liver function?

A. Propoxyphene 
B. Meperidine 
C. Tapentadol 
D. Oxymorphone
A

Propoxyphene

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12
Q

The metabolism of codeine into morphine can be blocked by

A. SSRIs
B. benzodiazepines
C. antipsychotics
D. lithium

A

SSRIs

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13
Q

Dull, diffuse pain signals are transmitted via __________ fibers.

A. A-delta 
B. C-delta 
C. C 
D. A-beta
A

C

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14
Q

Which of the orders below describes the level of opiate potency, from lowest to highest?

A. Opium, heroin, morphine 
B. Opium, morphine, heroin
C. Heroin, morphine, opium
D. Morphine, heroin, opium
A

Opium, morphine, heroin

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15
Q

Combining acetaminophen with alcohol is dangerous because it can result in

A. Hepatotoxicity 
B. Psychosis 
C. Pulmonary embolism 
D. Tachycardia
A

Hepatotoxicity

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16
Q

Aside from analgesia, what is the other primary indication for hydrocodone?

A. Sleep aid 
B. Muscle relaxant 
C. Cough suppressant 
D. Hypotension
A

Cough suppressant

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17
Q

Inhibition of COX-1 results in

A. Antipyresis
B. Analgesia 
C. Upset stomach 
D. Reduced inflammation
A

Upset stomach

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18
Q

Fentanyl is at least ____ times more potent than morphine

A. 40
B. 20
C. 60
D. 80

A

80

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19
Q

What is the #1 cause of acute liver failure?

A

Taking too much acetaminophen

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20
Q

True/False: You can take Tylenol for a hangover

A

FALSE

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21
Q

True/False: ibuprofen (Advil) is found in breast milk

A

FALSE

22
Q

True/False: concurrent administration of ketorolac (Toradol) with morphine can decrease morphine requirement

A

TRUE

23
Q

True/False: Indomethin (Indocin) has an increased side-effect liability

A

TRUE

24
Q

True/False: Sulindac (Clinoril) causes less GI upset than indomethin

A

TRUE

25
Q

What kind of preparations are available for diclofenac (Voltaren)?

A

delayed release, topical, and skin patch

26
Q

True/false: nabumetone (Relafen) is recommended for long-term treatment

A

TRUE

27
Q

True/False: Celecoxib (celebrex) has no cardioprotective effects

A

True, in fact it can actually increase risk.

28
Q

What are some common side effects of morphine?

A

respiratory
depression, pupillary
constriction, constipation,
decreased sex drive/fertility
problems, itching

29
Q

______ is metabolized to morphine (CYP 2D6). SSRIs can block this transformation

A

Codeine

30
Q

_____ is often mixed with acetaminophen (i.e., Vicodin, Norco)

A
31
Q

Hydrocodone is used for ________

A

mild-moderate pain, cough suppression

32
Q

___ is one of the most frequently abused prescription drugs in the USA

A

hydrocodone

33
Q

___ causes increased lipid solubility

A

heroin

34
Q

___ is 3x more potent than morphine

A

heroin

35
Q

___ has 6-10x the potency of morphine

A

hydromorphone/oxymorphone

36
Q

___ and ___ may inhibit the effects of hydromorphone/oxymorphone

A

antihistamines, MAOIs

37
Q

___ has greater euphoric effects than morphine

A

meperidine

38
Q

methadone has a half life of ___

A

24-36 hrs

39
Q

levo-alpha acetylmaethadol has a half life of ___

A

2.5 days

40
Q

levo-alpha acetylmaethadol has an increased risk of ____

A

cardiac effects

41
Q

___has a lower risk of dependence

A

propoxyphene

42
Q

___ is a good choice for poor metabolizers

A

propoxyphene

43
Q

___ has 80-500x the potency of morphine

A

fentanyl

44
Q

___ is used for opioid dependency through suppression of craving and decreased euphoria.

A

buprenorphine

45
Q

___ is a a combo of buprenorphine and naloxone. It treats opioid dependency without risk of abuse.

A

suboxone

46
Q

___ is a Mu agonist and blocks NET

A

tapentadol

47
Q

pentazocine has a __ risk of dependence or respiratory depression

A

LOW

48
Q

___ reverses respiratory depression caused by opiate OD. It lasts longer than naloxone

A

naloxone

49
Q

naltrexone is used to treat ___

A

opioid and alcohol dependence

50
Q

methylnaltrexone/alvimopan does not cross the blood brain barrier, it only has peripheral effects

A

TRUE

Psychopharm Final (8 decks)

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