week 13 asthma and inflammation

Question 1

what do asthma patients experience

Answer 1

increase residual volume and decrease in forced expiratory volume

Question 2

what are the two things that happen in someone who has asthma

Answer 2

the lining of the airways becomes red and swollen (inflammation)
the smooth muscle around the airways tighten

Question 3

what are the 4 main categories of things that cause asthma attacks

Answer 3

allergens
irritants
exercise
viral infections

Question 4

what are some aspects of the early phase of asthma pathogenesis

Answer 4

• bronchoconstriction

Question 5

what are some aspects of the late phase of asthma pathogenesis

Answer 5

• inflammation
  such as mucus hypersecretion
• airway hyper-responsiveness

Question 6

what are the 2 pharmacological interventions

Answer 6

• relievers (bronchodilators

- preventors (anti-inflammatory) stops it

Question 7

what are the main relievers

Answer 7

• inhaled beta 2 agonists
  they cause smooth muscle relaxation
  SABA - short-acting beta 2 recptor agonist causes bronchodilation 2-5 hours VENTOLIN
  LABA - long acting beta 2 receptors
  12+ takes 40min to react
• methylxanthines
  can easily reach toxicity so not as commonly used
• muscarinic antagonist
  prevent by another mechanism bronchodilator

Question 8

what are the main preventors

Answer 8

• leukotriene antagonist
  relaxes smooth muscle
• corticosteriods
  blocks inflammation

Question 9

what are the relievers for people who are very sensitive to and need more the other relievers and preventors?

Answer 9

• antibody treatment to immunoglobin which reduces the stimulations of mast cells and release of inflammatory mediators