Week 12 Flashcards
Staphylococcus Aureus - causes 4 diseases
1) Localized abscess (skin/bone)
2) Sepsis + acute endocarditis
3) hospital-aquirred and post-influenzal pneumonia
4) toxin-associated syndromes
Abscess to bone
Osteomyelitis
Staphylococcus Aureus - shape
cocci
Staphylococcus Aureus - gram status
gram positive
Staphylococcus Aureus - virulence factors (3)
- cell wall
- protein A (inhibits phagocytosis)
- membrane damaging exotoxins
Folliculitis - what
when hair follicles become inflammed
Folliculitis - cause
bacterial or fungal infection
Folliculitis - symptoms
- small red bumps or white headed pimbles around hair follicles
- can spread and turn into nonhealing crusty sores
- tenderness/itchiness at site
Folliculitis - complications
- Furnicle (abscess/deep pustule)
- Carbuncle (a group of follicles that coalece into one painful infected area)
Folliculitis - common names (3)
- hot tub rash
- razor bumps
- barber’s itch
Staphyloccocal Scaled Skin Syndrome - what
- diffuse, scarlet fever-like rash
- deeper skin infection
Staphyloccocal Scaled Skin Syndrome - pathogenesis
superficial layers of epidermis are separated and shed in sheds
- caused by hematologic spread of toxins from focal infection (nasopharynx, superficial skin abrasion)
Staphyloccocal Scaled Skin Syndrome - at risk population
children under 5
Staphyloccocal Scaled Skin Syndrome - symptoms (5)
- scarlet fever-like rash
- malaise
- fever
- irritability
- extreme tenderness over the skin
Bullous Impetigo - pathogenesis
- a thin blister that erupts and appears to be cloudy
- eventually rupture and crust
- caused by staphylococcus
Where are Bullous Impetigo found (4)
- trunk
- axilla
- extremities
- diaper area
Methicillin Resistant Staph Aureus - what
a bacteria resistant to several antibiotics
Methicillin Resistant Staph Aureus - complications
- pneumonia
- surgical site infections
- sepsis
- death
Methicillin Resistant Staph Aureus - risk
areas like hospital and nursing home - causes outbreaks
Methicillin Resistant Staph Aureus - transmission
- direct contact with an infected wound
- contaminated hands (of HCP)
- contact with MRSA carriers
Methicillin Resistant Staph Aureus - diagnosis
culture of bacteria
Group A beta-hemolytic streptococci - infects what
- skin and soft tissue infections
Group A beta-hemolytic streptococci - types of skin infections
1) impetigo
2) celulitis
3) erysipelas
4) necrotizing faciitis, non gas forming
impetigo
reddish sores on the face, especially around the nose and mouth and on the hands and feet.
Celulitis
a common bacterial skin infection that causes redness, swelling, and pain in the infected area of the skin
erysipelas
a skin infection involving the dermis layer of the skin, but it may also extend to the superficial cutaneous lymphatics. It is characterized by an area of erythema that is well demarcated, raised, and often affects the lower extremities, with the face being the second most commonly affected site.
Necrotizing facitis
- flesh eating disease
Group A beta-hemolytic streptococci - gram status
gram positive
Group A beta-hemolytic streptococci - oxygen status
aerotolerant (no oxygen)
Group A beta-hemolytic streptococci - virulence factors (3)
- capsule containing hyaluronic acid
- fimbriae
- exotoxins
impetigo - common group
infants and young children
impetigo - common season
warm summer months, warm moist climates
impetigo - contributing factors (2)
- overcrowded housing
- poor hygeine
impetigo - presentation
small vesicle or pustule or bulla on the face (can occur elsewhere)
impetigo - pathogenesis (3)
- small vesicle or pustule or bulla on the face (can occur elsewhere)
- primary lesion ruptures and leaves area that discharges honoey coloured liquid that hardens and crusts
- new vessicles erupt in hours, and pruitis causes scratching to multiply infection sites
Erysipelas - what
- infection of upper layers of the skin
- group a streptococcus
- fiery red rask with raised edges
- warm to touch
Erysipelas - pathogenesis
- minor traua (bruise, burn, wound, incision)
- rash then appears on trunk, arm, legs at localized lesion
Erysipelas - symptoms
- firery rash
- high fever
- chills
- headache
- nausea
- malaise
Cellulitis - what
- deper infection affecting dermis and subcutaneous tissues
Cellulitis - common sites
legs
hands
pinnae of ears
Cellulitis - rash
lesion consisting of expanding red, swollen, tender plaque with indefinite border, covering a small to wide area
Cellulitis - accompaning symptoms
- lesion
- fever
- erythema
- heat
- edema
- papin
Cellulitis - complications
- septicemia
- nephritis
- death
Measles: which virus
morbillivirus