Week 1 Flashcards

1
Q

What are pathogenic microorganisms (5 types)

A
  • bacteria
  • virus
  • parasite
  • fungi
  • parasitic protozoa
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2
Q

The pathogens that cause serious human infections (3)

A

BACTERIA is number one
then worms
then viruses

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3
Q

10 most burdensome infectious diseases in ontario

A
  • hepatitis C virus
  • streptococcus pneumoniae
  • Human papillomavirus (HPV)
  • Hepatitis B virus
  • E. coli
  • HIV/AIDS
  • staphylococcus aureus
  • influenza
  • clostridium difficile
  • rhinovirus
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4
Q

Leading cause of death - higher income

A

lower respiratory infections are the only to make the list

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5
Q

Leading cause of death - lower income

A

5/10 are infections (lower respiratory, diarrhoeal, malaria, TB, HIV/AIDS,

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6
Q

Social determinants of health + infectious disease

A
  • when inequities are high, community assets low, health outcomes are WORST
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7
Q

Endemic Disease

A
  • disease is always present in a population within a region
  • “expected” levels
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8
Q

Epidemic (1)

A

a rapid increase in cases higher than expected in a population within a region

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9
Q

Epidemic examples

A
  • EX SARS, Ebola, Cholera
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10
Q

Pandemic

A

an epidemic that becomes widespread over several regions, countries, continents

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11
Q

Outbreak

A

epidemic on a MUCH smaller scale (ex hospital floor)

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12
Q

Chain of infection

A

Infectious agent –> resevoir –> portal of exit –> mode of transmission –> portal of entry –> susceptible host

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13
Q

Resevoir

A

habitat where organism grows, lives, multiplies
- people
- equipment
- water
- animal

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14
Q

Portal of exit

A

means to leave the body
- excretions
- secretions
- droplets

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15
Q

Mode of transmission

A
  • contact
  • droplet
  • airborne
  • vector-borne
  • vehicle-borne
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16
Q

Portal of entry

A
  • respiratory tract
  • GI tract
  • Mucous membranes
  • skin
17
Q

Susceptible host

A
  • people with chronic disease
  • immunocompromised
  • very young
  • elderly
18
Q

Opportunities to break chain of infection

A
  • infectious agent is eliminated
  • portal of exit is managed via IPC practices
  • transmission does not occure due to IPC
  • portal of entry is protected
  • reducing susceptibility of patients recieving healthcare
19
Q

Infectious agent is eliminated:

A
  • rapid identification and management of organisms
  • clean and disinfect environement
20
Q

Portal of exit is managed

A
  • hand hygeine
  • PPE
  • safe packaging
  • disposal of waste
21
Q

Transmission does not occur

A
  • hand hygeine
  • isolation of infected patients
  • air flow control
22
Q

Portal of entry is protected

A
  • aseptic non-touch tequnique
  • safe catheter care
  • wound care
23
Q

reduce susceptibility of patients

A
  • treatment of underlying disease
  • recognize high risk patients
24
Q

Host-pathogen relationship - 3 factors

A

1) number of organisms in or on the host (higher = greater risk)
2) virulence of the organism
3) host defenses or degree of resistance

25
Virrulence
capacity of a microbe to cause disease
26
Why do some pathogens cause disease and others don't
- Virulence (ability of organism to cause infectious disease) - some infectious agents are easily transmitted but not very likely to cause disease (Ex polio) - other infectious agents are very virulent, but not terribly contagious (ebola)
27
Virulence factors of pathogens
1) flagella , pili, capsules 2) exotoxins and endotoxins
28
Flagella
tails on bacteria for movement
29
Pili
aka fimbrae short straight filaments that allow pathogens to bind to cells
30
Capsules
sugar coating on pathogens that make macrophages unable to target them
31
Exotoxins
exert biological effect on host cells EX neurotoxins cause paralysis others cause diarrhea, etc. pyrogenic toxins = cause fever and rash
32
Endotoxins
- lipopolysachuride, gram - bacteria - cause fever, malaise, etc.
33
Host susceptibility (5)
- immune system - age - nutrition - genetic defects - medications (ex chemo)
34
Host resistance (3)
- Barriers (epithelial layer, resp and GI tract,) - Chemical (tears, saliva, gastric juice) - Immunity against a particular agent (vaccines, antibody, etc.)