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csb202 > Week 10B - Aging > Flashcards

Week 10B - Aging Flashcards

1
Q

What factors have contributed to life expectancy extension?

A
  • Medical technology
  • Clean water
  • Food/agriculture
  • Protection from predators
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2
Q

What is Senescence?

A

The point at which cells stop dividing

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3
Q

What is the Hayflick Limit?

A

The maximum number of times a cell divides

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4
Q

What is a telomere?

A

-Natural end of chromosome (CCCTAA x250-1500)

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5
Q

Explain how telomeres cause senescence.

A
  • Telomeres grow shorter with each replication as DNA replication is not quite precise
  • When telomeres become very short proteins detect this and signal cells to stop dividing to prevent damage to the DNA
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6
Q

What protein extends telomeres?

A

Telomerase

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7
Q

What is anoerexia nervosa?

A

Eating disorder characterized by extremely low body weight/distorted self-image

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8
Q

How is calorie restriction proven to extend life span?

A
  • Calorie restriction activates sirtuin protein

- Sirtuin is responsible for keeping DNA stable

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csb202 (15 decks)

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