Week 10 Flashcards
chronic diseases are characterized by… (7)
- uncertain etiology
- multiple risk factors
- long latency period
- prolonged course of illness
- non-contagious origin
- functional impairement or disability
- incurability
what are the leading chronic diseases in Canada? (4)
- cancer
- CVS disease
- diabetes
- resp illness
what are consequences of chronic disease (4)
- reduced QOL
- family stress
- financial costs
- loss of productivity
define: rate
- a measure of the freq of a health event in a specific population in a defined time period
ex. 9.5 births per 1000 population for a year
define: incidence rate
- new cases during a certain time period (i.e. calendar year)
define: incidence rate
- new cases during a certain time period (i.e. calendar year)
define: attack rate
- new cases during communicable disease outbreaks
define: prevalence rate
- amount of total cases
prevalence rate is influenced by.. (3)
- incidence
- recovery
- death
define: risk
- probability that an event will occur within a specified period to determine morbidity and mortality.
how is risk calculated
Risk= # times something happens/# opportunities for it to happen
define: relative risk
- a measure of the probability of the occurrence of a disease for persons who are exposed and persons who are not exposed to the risk factor.
define: attributable risk
- a measure of the incidence of a disease in individuals who have been exposed to the risk factor, expressed as a percentage. AR= incidence rate in exposed group – incidence rate in non exposed group.
how is attributable risk calculated?
AR= incidence rate in exposed group – incidence rate in non exposed group.
In % = AR/Incidence rate in exposed group x100
define: population attributable risk
Result would show what decrease in incidence you would expect if people stop smoking for instance.
how is population attributable risk calculated
overall incidence rate – incidence rate of non-exposed group x 100.000
. In percentage: (overall incidence – incidence in non-exposed / overall incidence rate x 100
define: cancer
- A complex family of neoplastic diseases characterized by aberrations of cellular growth that causes abnormal proliferating cells to invade or destroy normal tissue.
who should screen via breast check and how often
- 50-74 yo
- every 2 years
who should screen via cervix check and how often
- 21-69 yo
- every 3 years
who should screen for colon cancer and how often? how?
- 50-74 yo
- every 2 years
- stool first, colonoscopy with risk factors q5years
what is the leading cause of premature death in Canada in both males and females
- cancer (has overtaken CVS disease)
approximately __% of all cancer incidence is related to preventable causes
50%
what are the most common types of cancer (3)
- lung
- breast
- prostate
(excluding non-melanoma skin cancer)
what are modifiable risk factors for cancer (10)
- smoking
- diet
- activity lvls
- microbes
- HPV
- alcohol
- sun exposure/UV radiation
- occupational exposures
- enviro exposures
- epigenetics
there is a strong causal link between smoking and…
- cancer
smoking is responsible for __% of all potential years of life lost due to cancer
27%
diet accounts for __% of cancers in developed countries
30%
what kind of diet is protective of cancer
- high fruit & veggie intake
describe the role of additives, substitues, residues, specific nutrients, or food groups r/t cancer
- unclear
high activity lvls reduce the risk of specific cancers such as… (3)
- colon
- breast
- prostate
what are direct and indirect benefits of activity r/t cancer (2)
- healthy body weight
- increases gut motility = reduced exposure to potential mutagens
excess weight increases amts of… (3)
- circulating estrogen
- androgens
- insulin
microbes are related to __% of cancers worldwide
15%
what are examples of microbes that can cause cancer (3)
- HPV
- herpes 2
- hep B
HPV is now considered the necessary cause for _____ and is found in __% of cases
- cervical cancer
- found in tissues of 90% of cases
what are examples of microbes that can cause cancer
- HPV
- herpes 2
- hep B
HPV also poses a risk for…
- oral cancer (HPV 16)
HPV also poses a risk for…
- oral cancer (HPV 16)
hep B virus is associated with 80% of all cases of ____ cancer worldwide
liver
increased consumption of alcohol causes…
- increased risk of cancer
alcohol is related to which kinds of cancer? (5)
- liver
- stomach
- breast
- colorectal
- mouth, pharynx, larynx, esophagus, and interacts w tobacco
sun exposure is related to..
- UV radiation
sun exposure increases the risk for which types of cancers? (3)
- basal cell carcinoma
- squamous cell carcinoma
- melanoma
what are examples of occupational exposures r/t increased risk of cancer (4)
- asbestos
- x-ray
- miners
- fireman
what are examples of enviro exposures r/t increased risk of cancer (2)
- radon
- BPA
define: epigenetics
- medication during pregnancy changing genes & increasing risks
- meds and behaviors changing genes
what is an example of how epigenetics can increase the risk of cancer
- in the 1970s, daughters of mothers who had taken Diethylstilbestrol (synthetic estrogen) during pregnancy were at high risk of a rare form of vaginal cancer
what are the risks for lung cancer (11)
- tobacco
- 2nd hand smoke
- air pollution
- ionizing radiation
- radon exposure
- occupational exposures (specific chemicals, fine dust)
- insufficient fruit/veggie consumption
- air pollution
- asbestos exposure
- personal history to lung disease
- genetic history
what are risk factors for breast cancer for females (10)
- age
- FHx
- atypical breast hyperplasis
- high education attainment
- high socio economic status
- excessive alcohol consumptions
- dietary fat
- ionizing radiation
- physical inactivity
- prolonged exposure to estrogen
what can lead to prolonged exposure to estrogen (5)
- Early menstruation/Late menopause
- Null parity
- First child born after age 30
- Post-menopause estrogen & progestin use
- Obesity after menopause
what are protective actions for breast cancer in women (2)
- breast feeding
- early children
what are risk factors for breast cancer in males (6)
- Age
- Family history
- Radiation exposure
- High estrogen levels
- Gynecomastia
- Obesity
what can cause high estrogen lvls in males
- genetic
- therapeutic
what are health promotion activities r/t breast cancer (5)
- non smoking –> smoking cessation
- diet –> cooking programs
- activity –> workout programs
- self screening
- provincial screen program and screening at the doctor
what are risk factors for prostate cancer (11)
- Prostatic hyperplasia
- Family history
- High fat diet
- Obesity
- Hormonal factors
- Herpes 2 infection
- Smoking
- Alcohol
- Physical activity
- Race(black men more in US)
- Screening at the doctor
what are risk factors for colorectal cancer (7)
- Family history
- Inflammatory bowel disease
- High fat, low fibre/vegetable/fruits diet
- Physical inactivity
- Alcohol consumption
- Obesity
- Smoking
what is included in secondary prevention for cancer
- screening for cervical, breast, and colon cancer screening
describe the prevention of CVS disease
- largely preventable as a great deal is known about etiology and risk factors
describe the impact of CVS disease (3)
- leading cause of death
- major cause of hospitalization
- significant impact on QOL
the prevalence of CVS diseases rises with…
- age