Week 1 Objectives 6: Compare spermatogenesis with oogenesis, summarize major steps in spermiogenesis Flashcards
Spermatogonia
2N Type A (stem cells) Type B: Leave mitotic cycle and enter meiotic cycle under influence of retinoic acid
Primary Spermatocytes
Undergoes Meiosis I —> Secondary Spermatocytes
Hyalurodinase
acrosomal enzyme
Spermiogenesis (SECOND TWO)
Acrosomal Phase 1. rotation of acrosomal pole toward wall of seminiferous tubule 2. Cytoplasm displaced toward tail Maturation phase 1. completion of flagellum 2. completion of nuclear condensation
Spermiogenesis (FIRST TWO)
- Golgi phase a. Proacrosomal vesciles b. acrosomal vesciles 2. Cap phase a. mature acrosomes form cap over nucleus
Structure of the Testis
Primitive sex cords Seminiferous tubules 1. Spermatagonia cells 2. Sertoli cells Cells of Leydig (interstital cells) 1. Produce testosterone
Zona lysin
acrosomal enzymes (in mammalian sperm)
Primordial Germ Cells
diploid (2N)
Sequence of cell types, meiotic events, and chromosomal complement in spermatogenesis
- Spermatogonium: 2n, 4c —> I I V 2. Primary Spermatocyte —> 2n, 4C Meiosis 3. Two haploid Secondary Spermatocytes —> n, 2C Meiosis II 4. Four haploid Spermatids —> n, 1c I V Spermiogenesis —> Spermatazoa (4 haploid gametes)
Spermatids
4 haploid cells
Spermiogenesis: acrosomal enzymes
synthesized under influence of mRNA during pre-leptotene stage
Sperm histones
proamines
Secondary Spermatocytes
haploid, 2 cells, begins meiosis II