Week 1 Nuggets

Question 1

What’s the differential diagnosis for acute inflammatory mono arthritis?

Answer 1

bacterial arthritislyme diseasegonococcal arthritisreactive spondyloarthritisgouttrauma

Question 2

What would expect of the cell count from a inflamed v. an infected joint.

Answer 2

inflammation: >2K-50Kinfection >100,000

Question 3

What is the d/dx for an inflammatory polyarthritis?

Answer 3

RASjogrenLupusSpondyloarthrits

Question 4

What is the d/dx for inflammatory mono arthritis?

Answer 4

gout, psuedogout, septic arthritis OA (bland)

Question 5

How do you tell the difference between polymyalgia rheumatica and myositis?

Answer 5

no CK elevations for true myositisPM is very responsive to steroids

Question 6

What is the D/dx of a patient presenting with signs of systemic process (rash, lung symptoms) with polyarthritis of the small joints?

Answer 6

lupusRAViral (esp. parvo)hepatitisrubellaCMV

Question 7

Which test is most sensitive for lupus?

Answer 7

ANA, antinuclear antibody (CTD)Smith (highly specific)

Question 8

cANCA+ makes you consider which disease?

Answer 8

Granulmoatosis with polyangitis