Week 1 Lec: Intro to Hema Flashcards

1
Q

Define Hematology.

A
  • Study of the disorder and abnormalities related or associated with the quality and quantity of the cellular elements of the blood
  • Study of the laboratory procedure and techniques being used to examine the quality and quantity of the cellular elements of the blood
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2
Q

1657

A

describe worms in the blood by Athanasius Kircher

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3
Q

1658

A

discovery of erythrocytes by Swammerdam

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4
Q

1674

A

human erythrocytes described by Van Leuwenhoek

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5
Q

1842

A

platelets were described

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6
Q

1846

A

PMN distinguished from other leukocytes by Wharton Jones

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7
Q

1879

A

first complete classification of leukocytes by Ehrlich

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8
Q

1902

A

development of Wrights stain by James Homer Wright

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9
Q

1920

A

hematology was considered a separate science from clinical pathology

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10
Q

A

A

without

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11
Q

blast

A

youngest/nucleated

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12
Q

-chromic

A

color

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13
Q

-cyte

A

cell

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14
Q

Dys

A

abnormal

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15
Q

-emia

A

in the blood

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16
Q

Ferro

A

iron

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17
Q

Hyper

A

increased

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18
Q

Hypo

A

decreased

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19
Q

Iso

A

equal

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20
Q

Macro

A

large

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21
Q

Mega

A

very large/huge

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22
Q

Micro

A

small

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23
Q

Myelo

A

marrow

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24
Q

Normo

A

normal

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25
Q

-oid

A

like

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26
Q

FBC

A

Full Blood Count

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27
Q

Fl

A

Femtoliter

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28
Q

Hb

A

Hemoglobin Concentration

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29
Q

Hct

A

Hematocrit

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30
Q

MCH

A

Mean Cell Hemoglobin

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31
Q

MCV

A

Mean Cell Volume

32
Q

MCHC

A

Mean Cell Hemoglobin Concentration

33
Q

CBC

A

Complete Blood Count

34
Q

PG

A

Picogram

35
Q

A life sustaining fluid which circulates through the heart and blood vessels.

A

Blood

36
Q

It carries oxygen and nutrients to the ________ and waste products to the _______,_______, and _______ where they can be removed from the body

A

tissues; lungs, liver and kidney

37
Q

What are the formed elements of blood?

A

erythrocytes, leukocytes, platelets, plasma

38
Q

It is the liquid portion of unclotted blood.

A

Plasma

39
Q

It is the fluid that remains after coagulation has occurred and clot has formed.

A

Serum

40
Q

What are the components of plasma?

A

90% water, proteins, hormones, enzymes, lipids, and salts

41
Q

Plasma appears?

A

hazy and pale yellow

42
Q

Serum appears?

A

clear and straw-colored

43
Q

Which has fibrinogen?

A

Plasma

44
Q

What is the percentage of plasma in total blood?

A

55%

45
Q

What is the percentage of erythrocytes in total blood?

A

45%

46
Q

What is the percentage of buffy coat in total blood?

A

<1%

47
Q

What is in the buffy coat of blood?

A

leukocytes and platelets

48
Q

In vivo, blood is?

A

fluid/liquid

49
Q

In vitro, blood?

A

coagulates in 5-10 minutes

50
Q

Blood is ________ times thicker than water.

A

3.5-4.5

51
Q

Blood makes up _____% of the total body component, or _____ml/kg.

A

6-8%, 60-80 ml/kg

52
Q

Amount of blood in gms solid/mL?

A

20 gms solid/100 mL

53
Q

TBV in adult male, female, and newborn, respectively?

A

5-6 L, 4-5 L, 250-350 mL

54
Q

It can be described as the thickness and stickness of blood.

A

Blood viscosity

55
Q

It is a measure of the resistance of blood to flow

A

Viscosity

56
Q

The viscosity of blood is __ times more than that of water.

A

5

57
Q

The viscosity and specific gravity of blood depends on?

A

RBCs and plasma proteins

58
Q

It is a measure of the acidity or basicity of an aqueous solution. It is the negative decimal logarithm of hydrogen concentration.

A

pH

59
Q

What is the normal pH range of blood?

A

7.35-7.45

60
Q

What is the average pH of blood?

A

7.40

61
Q

What is the pH of venous blood?

A

7.35

62
Q

What is the pH of arterial blood?

A

7.45

63
Q

How is pH of blood maintained?

A

excretion of CO2 by the lungs and excretion of H+ or OH by the kidney by the action of a buffer system (carbonate, phosphate, protein, hemoglobin)

64
Q

It is the ratio of the density of a substance to the density of a reference substance.

A

Blood Specific Gravity

65
Q

Specific gravity is also called?

A

relative density

66
Q

Number of solutes dissolved in whole blood?

A

1.045 – 1.066

67
Q

Number of solutes dissolved in serum?

A

1.024 – 1.028

68
Q

Number of solutes dissolved in plasma?

A

1.025-1.029

69
Q

Color of arterial blood?

A

bright red

70
Q

Color of venous blood?

A

dark purplish red

71
Q

In pulmonary arteries and veins, Hb with O2 is color?

A

purple

72
Q

In pulmonary arteries and veins, Hb without O2 is color?

A

blue

73
Q

What is the concentration of solutes dissolved in the blood called?

A

Osmolality

74
Q

What is used to measure osmolality?

A

Osmometer

75
Q

Reference range for osmolality is _______ mOsm/kg.

A

281-297 milliosmoles per kilogram

76
Q

Give the 7 functions of blood.

A
  1. RESPIRATORY
  2. NUTRITIONAL
  3. EXCRETORY
  4. BUFFERING ACTION
  5. MAINTENANCE OF CONSTANT BODY TEMPERATURE
  6. TRANSPORTATION OF HORMONES AND OTHER ENDOCRINE SECRETION THAT REGULATES CELL FUNCTION
  7. BODY DEFENSE MECHANISM