Week 1 and 2 topics

Question 1

any substance (except
food and water) when taken into
the body alters the body’s
function either physically and/or
psychologically

Therapeutic agent; any substance, other than
food, used in the prevention, diagnosis,
alleviation, treatment, or cure of disease.
* A substance recognized by an official
pharmacopoeia or formulary. A substance
intended for use in the diagnosis, cure,
mitigation, treatment, or prevention of
disease. A substance (other than food) intended to
affect the structure or any function of the body.

Answer 1

Drug

Question 2

:A finished dosage
form, for example, a tablet, capsule or
solution that contains an active
pharmaceutical ingredient, generally,
but not necessarily, in association with
inactive ingredients.

Answer 2

Pharmaceutical (product)

Question 3

: any
substance or mixture of substances intended to be used in the
manufacture of a drug (medicinal) product and that, when used
in the production of a drug, becomes an active ingredient. They
produce pharmacological activity or other direct effect in
diagnosis, cure, mitigation, treatment or prevention of disease
or to affect the structure or function of the body.

Answer 3

Active Pharmaceutical Ingredient (API):

Question 4

component of the finished product other than API,
examples are fillers, colorants, flavorants, solvents, preservatives.

Answer 4

Excipients:

Question 5

Top 1-3 list of Top Pharmaceutical Companies in the Philippines

Answer 5

Top 1: Pfizer
top 2: AstraZeneca Philippines
top 3: Eli Lill and Company

Question 6

Top 4-6 list of Top Pharmaceutical Companies in the Philippines

Answer 6

4: GlaxoSmithKline
5: Merck, Sharp and Dohme
6: Novartis

Question 7

Top 7-10 list of Top Pharmaceutical Companies in the Philippines

Answer 7

7: Roche
8: Sanofi-Aventis Philippines
9: United Laboratories
10: Wyeth

Question 8

Others list of Top Pharmaceutical Companies in the Philippines

Answer 8

Abbott
Johnson &Johnson
Boehringher Ingelheim
Bristol Myers Squibb
Bayer
Pascual Laboratories
Schering Plough
InnoGen Pharma Group Inc
Natrapharm
GV International
Euro-Med Lab
Baxter TC Pharma Ind.
International Pharma
Getz Pharma
Interphil Laboratories

Question 9

other term for Prescription Drug?

Answer 9

Ethical Drugs

Question 10

Top 1-10 Prescription Drug Brands

Answer 10

1: Novarsc [Pfizer]
2: Ventolin [Glaxo-SK]
3: Plavix [Sanofi-Aventis]
4: Augmentin [Glaxo-SK]
5: Neobloc [GX International]
6: Lipitor[Pfizer]
7: Tazocin [Wyeth]
8: Zegen [United American UL]
9: plendil [AstraZeneca]
10: Seretide [Glaxo-SK]

Question 11

Novarsc [Pfizer] Indication and Generic name ?

Answer 11

: Hypertension
: Amlodipine

Question 12

Ventolin [Glaxo-SK] indication and Generic name ?

Answer 12

: Asthma
: Albuterol/ salbutamol

Question 13

Plavix [Sanofi-Aventis] indication and Generic name?

Answer 13

: Thrombosis/ Anti-platelet
:Clopidogrel

Question 14

Augmentin [Glaxo-SK] indication and Generic name?

Answer 14

: Infection/ Antibiotic
: Amoxicillin / Clavulanic acid

Question 15

Neobloc [GX International] indication and Generic name?

Answer 15

:Hypertension
: metoprolol

Question 16

Lipitor[Pfizer] indication and Generic name?

Answer 16

:hypercholesterolemia/ Anti-cholesterol
: Atorvastatin

Question 17

Tazocin [Wyeth] indication and Generic name?

Answer 17

: infection
:tazobactam

Question 18

Zegen [United American UL] indication and Generic name?

Answer 18

: infection
: Cefuroxime axetil

Question 19

plendil [AstraZeneca]

Answer 19

:Hypertension
: Felodipine

Question 20

Seretide [Glaxo-SK] Indication and Generic name ?

Answer 20

: Asthma
:Salmeterol + Fluticasone

Question 21

Generic name of Xenical?

Answer 21

Orlistat

Question 22

Top 1-10 OTC BRAND in PH

Answer 22

1: Ceelin [Pediatrica]
2: Solmux [Westmont]
3: Neozep [Myra]
4: Biogesic [Biomedis]
5: Enervon [United American]
6: Alaxan [Therapharma]
7: Myra E [Myra]
8: Xenical [Roche]
9: Centrum [Wyeth]
10: Cherifer [Gx Pharma]

Question 23

Ceelin
Enervon
Myra E
Centrum
Cherifer

OTC drugs indication?

Answer 23

vitamin Supplement

Question 24

Does OTC drug Neozeop have potential to increase blood pleasure?

Answer 24

true

Question 25

a detailed examination of anything complex in
order to understand its nature or to determine its
essential features : a thorough study

Answer 25

Analysis

Question 26

defined as the application of analytical procedures used to
determine the purity, safety and quality of drugs and chemicals

• A branch of chemistry, which involves the series of
  process for the identification, determination,
  quantitation, and purification.
• This is mainly used for the separation of the
  components from the mixture and for the
  determination of the structure of the compounds

Answer 26

Pharmaceutical Analysis

Question 27

two main types of Analysis:

Answer 27

Qualitative And Quantitative

Question 28

• What is in the sample?
  Identification
  Composition determination
  Ascertainment of impurities

Answer 28

Qualitative Chemistry

Question 29

How much is in the sample?
determination of the proportion of
components in a substance

Answer 29

Quantitative chemistry

Question 30

Analysis of purity and quality of drugs and chemicals used in practice.

Others: applied in throughout industry,
medicine, environment
- Analysis of the chemical
constituents found in human body.
- Analysis of medicinal agents and
their metabolites found in biological system

Answer 30

Qualitative–Quantitative
Chemistry in Pharmacy

Question 31

Classification of Analysis

Answer 31

Based on sample size
II. Based on the extent of determination
III. Based on nature of methods
IV. Based on materials used

Question 32

Based on sample size: < 1 mg

Answer 32

Ultramicroanalysis

Question 33

Based on sample size: 1 mg-– 10 mg

Answer 33

Microanalysis

Question 34

Based on sample size: 10 mg- 100mg

Answer 34

Semi-microanalysis

Question 35

Based on sample size: 100 mg – 1 g

Answer 35

Macroanalysis

Question 36

Based on the extent of
determination: Total amount of a class or a group of
active plant principles in a given
sample.

Answer 36

Proximate analysis

Question 37

Based on the extent of
determination: Amount of a specific constituent or a
single chemical species present in the
sample

Answer 37

Ultimate analysis

Question 38

Based on the nature of
methods: also known as general/ chemical/ wet/
stoichiometric method

Answer 38

Classical method

Question 39

Classical method examples?

Answer 39

titrimetric analysis
gravimetric analysis

Question 40

Based on the nature of methods: more accurate
* based on specific physical or
chemical properties of the analyte

Answer 40

Instrumental method

Question 41

Instrumental method: s—Works by measuring the
potential (volts) and/or current (amps) in an
electrochemical cell containing the analyte

Answer 41

Electrochemical methods

Question 42

Instrumental method:—based upon the measurement of the
interaction of the molecules with electromagnetic
radiation

Answer 42

Optical methods

Question 43

Instrumental method:It is defined as the process of
separation of the individual components of a mixture
based on their relative affinities towards stationary and
mobile phases.

Answer 43

Chromatography