PHANLAB reviewer Flashcards
refers to the process of determining the POTENCY, STRENGTH, or PERCENTAGE PURITY of a drug.
Assay
-determination of the proportion of components in a given sample.
Quantitative method of analysis
involves the identification/ composition determination.
Qualitative method of analysis
It consist of determination of volume of solution of accurately known concentration required to react completely with the solution or substance to be determined.
Volumetric Analysis
Volumetric Analysis can also be?
Titrimetric method of analysis
Volumetric analysis is a method in which the amount of a substance is determined by measuring the volume that it occupies and the volume of a second substance that combines with the first in known______.
proportions
A solution of accurately known strength, usually expressed in terms of Molarity or Normality
Titrant or standard solution or volumetric solution
the substance being titrated, the active constituent being analyzed
Analyte or Titrand or Titrate
the point at which reaction between the analyte and the titrant is just completed. Indicated by change in the color of indicator
End point or Equivalent point
the process of addition of titrant from burette into the unknown concentration/analyte in the flask
Titration
It is a complex organic compound which shows clear visual change after the reaction between titrant and analyte is just completed
The visual changes is often cause by change of pH
Indicator/ test solution
– number of equivalents of solute per L of solution.
Normality (N)
number of moles of solute per L of solution.
Molarity (M)
number of moles of solute per Kg of SOLVENT
Molality (m)
Preparation and standardization of 1 N HCl: Titrant/ standard solution
1N HCl