Week 1 Flashcards
The “father” of immunology is generally considered to be:
Pasteur
Functions of the immune system are to:
1) Recognize self from nonself.
2) Defend the body against nonself.
The first line of defense against infection is:
Unbroken skin or mucous membranes
A specific component of the adaptive immune system formed in response to antigenic stimulation is
Immunoglobulins
Artificial passive immunity is achieved by:
Infusion/injection of preformed specific antibody.
Characteristics of clonal selection include:
1) Antigen binding to a unique antigen receptor site.
2) Activation of antigen-bound lymphocytes.
3) Proliferation of antigen-bound lymphocytes.
An antigen is described as a substance that:
1) Stimulates antibody formation.
2) Has the ability to bind to an antibody.
3) Is capable of stimulating an immune response.
The type of immunoglobulin involved in type I hypersensitivity reactions is:
IgE
List three characteristics of IgM.
1) It is produced during a primary antibody response.
2) It has the largest molecular weight of all the immunoglobulin classes.
3) It fixes complement
Which immunoglobulin (Ig) class is produced in the highest concentration in a secondary (anamnestic) response?
IgG
IgE is an important immunoglobulin because it:
1) Mediates some types of hypersensitivity (allergic) reactions.
2) Is generally responsible for an individual’s immunity to invading parasites.
3) Binds strongly to a receptor on mast cells and basophils and, with antigen, mediates the release of histamines and heparin from these cells.
Which region determines the class of an immunoglobulin molecule?
CH
A secondary function of an antibody is to:
Fix complement and to Transfer through the placenta.
Hematopoiesis occurs in the yolk sac during which stage of gestation?
Embryonic period of gestation.
The number of individual heavy chains found in a molecule of IgM is:
Five.
