wednesday 17th Flashcards
causes of metabolic alkalosis
hypokalaemia
loop diuretics
hyperaldosteronism
cushings
vomiting
liquorice
casues of a metabolic acidosis with raised anion gap
K- ketones: DKA, Alcohol
U- urate : renal failure
L - actate- sepsis, shock , hypoxia, metformin
T - toxins : salicylic,methanol
causes of a hyperchloreamic metabolic acidosis
addisons
diarrhoea
renal tubular acidosis
ureterosigmoidostomy
side effects of 5-ASA drugs
mesalazine - agranulocytosis, pancreatitis, headache
sulfa- oligospermia, headache, lung fibrosis
when shoudl prophylactic abx for SBP be offered? what one?
if ascitic protein <15g/l or had an episode of SBP
cipro
what neutrophil count is diagnostic of SBP
> 250
management of SBP
IV cefotaxime
symptoms of SBP
ascites, fever, pain
IX for budd chairir
USS with dopple flow
what hormones do renal cell carcinomas produce
EP, PTH, ACTH
what investigations should be done in a newly diagnosed cirrhotic patient
endoscopy for varices
USS for HCC(+AFP)
serum and urine osmolality findings in. SIADH
low serum osmol
high urine osmol - dumping all sodium
sodium high or low in diabetes insipidus
hypernatraemia
serum and urine osmolalities in SIADH vs DI
SIADH - low serum osmol , high urine osmol
DI- high serum osmol, low urine osmol
antibodies in addisons
anti-21-hydroxylase
when do you measure cortisol in a short synachten test- what is a normal result
before giving and after 30 mins - normally cortisol should double
most common cause of hyperaldosteronism
bilateral idiopathic adrenal hyperplasia
what test can differentiate between bilat idio adrenal hyperplasia and adrenal adenoma causing conns
adrenal venous sampling