monday 14th Flashcards

1
Q

what length of time determines if its A premature rupture of membranes

A

> 4hr between ROM and contractions = PROM

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2
Q

minimum dilatation for amniotomy

A

2cm

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3
Q

what type of decelrations are bad in labour on CTG

A

late decelerations reduced FHR for 15 beats fro 15 secs

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4
Q

a foetal scalp pH of what would indicate delivery

A

<7.2

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5
Q

after how long in maternal arrest do you deliver baby

A

3 mins

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6
Q

initial mangement in any maternal collapse

A

left tilt

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7
Q

how long does puerperium last

A

6 weeks post partum

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8
Q

the three types of dicharge post birth and how long they last + colour

A

rubra - red -3-4 days
serosa- brown - 4-14
alba- yellow - 10-20

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9
Q

what hormones in hibit milk production

A

progesterone adn oestrogen

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10
Q

how long should someone breastfeed for

A

first 6 months exclusively then add solids +breast for up to 2 years

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11
Q

causes adn treatment of mastitis

A

staph - aureus
continue breast feed plus analgesia
if sys unwell or does not improve for 2 days oral fluclox

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12
Q

where do abscesses unrelated to breast feeding tend to be

A

sub areolar

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13
Q

levels of PPH

A

minor = 500-1L
major > 1L or shock

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14
Q

how to work out someones blood volume

A

100ml per kg

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15
Q

mangement of PPH uterine atony

A
  • ABCDE
  • catheterise
  • bimanual massage
  • syntocin
  • ergometrine
    -carboprost
  • misoprostol
    -TXA ?
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16
Q

surgicla mangement of PPH

A

ballon
b-lynch sutures
artery ligation
hysterectomy

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17
Q

desrcibe degree of perineal tears

A

first - skin only
second - skin and levator ani
third- involving anal spinchter
fourth 0 involving sphincter and rectal mucosa

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18
Q

what level of tears require theatre

A

3rd and 4th

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19
Q

lifestsyle advice for stress incontinence

A

weight loss, smoking cessation, avoid constipation, heavy lifting avoid and reduce caffeine

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20
Q

treatment fo UTI in pregnant women

A

1/2 trimestetr - nitrofurantoin
3- trimepthoprim

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21
Q

role of sertoli cells

A

secrete aeminiferous fluid, androgen globuli, inhibin adn activin

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22
Q

role of leydig cells

A

secrete testpsterone

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23
Q

what pituitary hormone regulates spermatogeneisis

A

FSH

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24
Q

how can diabetes impact fertiliy

A

reduces testosetrone in men

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25
Q

what hormones are high in PCOS

A

LH and testosterone

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26
Q

describe duct system in breast

A

terminal ductules- intralobular collecting duct - lactiferous duct - lactiferous sinus - nipple

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27
Q

what is involved in breast triple assessment

A
  • clinical
  • imaging eg- mam, us , MRI
  • biopsy
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28
Q

blue doems breast lump with pale fluid

A

fibrocystic change

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29
Q

treatment of kawasaki

A

high dose aspirin
IVIG
do an echo

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30
Q

complications of kawaski

A

cornornary artery aneurysm

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31
Q

management of duct ectasia

A

abx
stop smoking
excise

32
Q

leaf breast tumout

A

phyloddes

33
Q

what breast cancer can be seen only through screening

A

intraductal papilloma

34
Q

what is the precursor to Ductal carcinoma in situ

A

intraductal papilloma

35
Q

what child rash causes spots on uvula and high fever with maculopapular rash

A

roseola infantum

36
Q

what virus casues roseola

A

HHV6

37
Q

most common complication of chicekn pox in adults

A

varicella pneumonia

38
Q

tx for impetigo

A

1% hydro peroxide

39
Q

diff between lobular carcinoma in situ and atypical lobular hyperplasia

A

atypical lobular hyperplasia <50% of lobule involved
in situ > =50% involved

40
Q

most common type of breast cancer

A

invasive ductal carcinoma

41
Q

what type of malignant breast cancer is not palpable and seen on mammogram

A

lobular in situ

42
Q

what type of breast cancer is more common ductal or lobular

A

ductal

43
Q

what is a DCIS called when it involves the nipple

A

pagets disease of nipple

44
Q

A DCIS of what size indicates mastectomy over wide local excision

A

> 4cm = mastectomy

45
Q

risk factors for breast cancer

A

nulliparity
early menarche, late meno
cocp
obestity
BRCA/p53

46
Q

examples fo anti oestrogen therapies

A

tamoxifen
aromatase inhibitors - letrozole/anastrozole
GnRh analogues - goserelin
oophrecetomy

47
Q

side effects of anti-oestrogen therapy in breast cancer

A

hot flushes
VTE
Endometrial cancer
menstrual disturbances

48
Q

side effects of aromatase inhibiots

A

osteoporosis
hot flushes
insomnia

49
Q

What therpay is used after breast cancer wide local excision

A

radiotherapy

50
Q

anti-oestrogen therapy used in pre and post menopausal women

A

pre- tamocifen
post-aromatse inhibitos (more effective so reserved for these women )

51
Q

what therapy is used in HER2+ve breats cancer and when is it contraindicated

A

trastuzamab (HERCEPTIN)
contra in hx of heart problems

52
Q

is +ve HER2 good or bad

A

BAD

53
Q

what is the best hormone profile to have in breast cancer

A

OE+, PR+ HER2-ve

54
Q

what therapy can be done pre-surgery in breast cancer

A

chemo

55
Q

do breast cancers have incresaed or decresaed vascularity

A

increased

56
Q

what is USS bad for seeing - breast cancer

A

DCIS

57
Q

difference between partial and complete mole

A

partial - 3 sets of DNA - 1 egg, 2 sperm - may have foetus
completet - no maternal DNA in egg -no foestu

58
Q

how long post molar pregancy before can get pregnant

A

12 months

59
Q

risk following molar preg

A

choriocarcinoma

60
Q

features of threatened misscariiage vs inevitble

A

threatened - closed os light bleeding
inevitable - open os - heavy bleed +clots

61
Q

what is a missed/delayed miscarriage

A

gestational sac present but no foetus

62
Q

what is classed as recurrent miscarriages

A

3 or more consec losses - screen for phosph and thrombophilia

63
Q

indications for medical or surgical miscarriage managment over conservative

A

increased risk of haemorrhage
prev traumatic experience eg still birth
infection

64
Q

medical management of miscarriage

A

vaginal misoprostol - see doctor if no bleeding in 24 hrs

65
Q

a b-HCG of what points towards ectopic preg

A

> 1,500

66
Q

indication for surgical management of ectopic

A

> 35mm
foetal heart beat
pain
hcg>5000

67
Q

if b-hecg >1000 but<1500 what management is indicated

A

medical amangeemnt - mehtotrexate- follow up

68
Q

pneumonia with hyponatraemia + deranged LFT and dx test

A

legionella - urine antigen test

69
Q

raised antibodies in autoimmune hepatitis

A

ANA/SMA/LKM1 antibodies, raised IgG levels

70
Q

plateelt transfusion thresholds

A

<30
<100 if significant bleeding

71
Q

how long after acute stroke should AF meds be started

A

2 weeks

72
Q

ECG changes in hyperkaalemis

A

tall t , widened QRS , flat p waves

73
Q

most common organism from line infections

A

staph epidermidis

74
Q

seizure following sleep deprivation

A

juvenile myoclonic epilepsy

75
Q

first line screening test in those with iron deficient anaemia

A

anti -ttg