WBC Anomalies/Abnormalities

Question 1

The stain used to identify Downey cell.

Answer 1

Pyronine stain (red)

Question 2

An abnormal reactive lymphocyte or virucyte with large cytoplasm than nucleus. Has pseudolobilations.

Answer 2

Downey cells

Question 3

Related to Kissing disease or Acute IM and EBV.

Answer 3

Downey cells

Question 4

A monocyte with a phagocytosed nucleus of a lymphocyte.

Answer 4

Tart cells

Question 5

Tart cells are present in patients with?

Answer 5

Drug sensitivity

Question 6

The affected organ of LE cells.

Answer 6

Kidney

Question 7

The disease present having the LE cells.

Answer 7

Lupus erythematosus (autoimmune disease)

Question 8

A phagocytic neutrophil with phagocytosed degenerative nuclear mass off another neutrophil.

Answer 8

L.E. Cells

Question 9

Ferrata cell is associated with what disease?

Answer 9

Subacute bacterial endocarditis (SBE)

Question 10

A abnormal lymphocyte with segmented/lobulated nucleus.

Answer 10

Rieder Cells

Question 11

This disease is observed in Rieder cell abnormality.

Answer 11

Chronic Lymphocytic Leukemia (CLL)

Question 12

A thin, thread like structure arising from the nucleus associated with Malignant abnormal changes.

Answer 12

Hairy Cell

Question 13

Stain used to identify Hairy cell leukemia.

Answer 13

TRAP

Question 14

Similar to plasma cell, except of no cartwheel chromatin pattern.

Answer 14

Turk irritation cell

Question 15

Presence of 2 nucleus found in one cell.

Answer 15

Tuinning deformity

Question 16

Associated disease in Tuinning deformity.

Answer 16

Pernicious anemia

Question 17

Hyposegmentation described as “Pince-nez” or “Dumbbell shaped”.

Answer 17

Pelger-huet Anomaly

Question 18

Pince-nez is a congenital failure that can be seen in leukemia on what kind of cell?

Answer 18

Neutrophil

Question 19

A blue colored inclusions seen in cytoplasm having large vacuole.

Answer 19

Dohle Amato bodies

Question 20

Thought to be remnants of Rough ER using Giemsa stain.

Answer 20

Dohle Amato Bodies

Question 21

Dohle Inclusion is present with patients having?

Answer 21

Toxic conditions, severe infections, burns and Chemotherapy

Question 22

Associated with Dwarfism or Gargoylism or Pfaunder hurler syndrome.

Answer 22

Alder Reilly Bodies

Question 23

Coarse azurophilic granules seen in granulocytes most commonly in neutrophils. Inherited as recessive trait.

Answer 23

Alder Reilly Bodies

Question 24

A sex chromatin of somatic cell (X-chromosome).

Answer 24

Barr Bodies

Question 25

A knob like structure arising from the lobe of neutrophil. Exclusive to females "Sexing of PMN".

Answer 25

Drum stick

Question 26

Jordan's Anomaly is commonly found in patients with?

Answer 26

Muscular dystrophy

Question 27

A fat containing granule observed in granulocyte and monocyte.

Answer 27

Jordan's Anomaly

Question 28

Similar to Dohle bodies but usually seen with Giant platelets.

Answer 28

May Hegglin Anomaly

Question 29

Characterized by the presence of Peroxidase + Dohle like bodies.

Answer 29

Chediak higashi syndrome

Question 30

Stains used to identify Czediak Higashi Syndrome.

Answer 30

Sudan black B, Acid phosphatase, and Peroxidase +

Question 31

Auer Rod is usually seen with patients having this disease.

Answer 31

Acute monocytic/myelocytic Leukemia

Question 32

A rod like structure seen in cytoplasm of monoblast and myeloblast.

Answer 32

Auer bodies or Auer Rod

Question 33

Platelets encricling the peripheral borders of neutrophil.

Answer 33

Platelet Satellitosis

Question 34

An abnormal neutrophil with 5-10 lobes seen mostly in Pernicious Anemia(Macrocytic normochromic).

Answer 34

Hypersegmented Neutrophil

Question 35

Thorn cell, Spur cell with 5-10 irreversible thorn like projections.

Answer 35

Acanthocytes

Question 36

Disease associated in Acanthocytes.

Answer 36

Hemolyic anemia, Alcoholic cirrhosis, and abetalipoproteinemia

Question 37

Reversible thorn like projections that increase when BUN increase.

Answer 37

Burr cell

Question 38

Occur in RBC placed under hypertonic NaCl solution.

Answer 38

Echinocyte or Crenated RBC

Question 39

Sausage shaped found in Pernicious Anemia or Hereditary Elliptocytosis.

Answer 39

Elliptocytes

Question 40

With thin peripheral cell membrane found in Microangiopathic H.A.

Answer 40

Keratocyte or Blister cell

Question 41

Round cells lacking central pallor related with Hereditary spherocytosis and Spectrin deficiency.

Answer 41

Spherocytes

Question 42

Slitlike central area of palor seen in Alcoholism and Rh null disease.

Answer 42

Stomatocytes or Mouth cell

Question 43

Helmet shaped. Fragmenting RBC, found in HA, severe burns, diffuse intravascular coagulation syndrome (DIC).

Answer 43

Schistocyte

Question 44

Tear drop cell typically observed thalassemia, Myelofibrosis, and Pernicious anemia.

Answer 44

Dacrocyte

Question 45

Similar to tear drop but with long tail.

Answer 45

Racket cell

Question 46

Also known as codocyte, mexican hat cell , platycytes, leptocyte , Greek helmet cell , bull’s eye cell. Comes from the greek word "Kodon=bell".

Answer 46

Target cell

Question 47

A star like RBC seen in certain anemias.

Answer 47

Astrocytes or Stellar cell

Question 48

Thin thread like structure in loop shape or figure of 8. Remnants of nuclear membrane (mitotic spindle).

Answer 48

Cabot rings

Question 49

Observed in patients with Pernicious anemia and Lead poisoning. Stains reddish purple with wright's stain.

Answer 49

Cabot rings

Question 50

A small round darkly staining body, remnants of the nucleus seen in HA, PA and after splenectomy. (DNA)

Answer 50

Howell-Jolly bodies

Question 51

A fine or coarse basophilic stipplings (ribosome) seen in RBC that normally loss upon cell maturation.Seen in Lead poisoning.

Answer 51

Basophilic Stippling

Question 52

Non-heme iron deposits found in the RBC, usually Prussian blue positive. Seen in Plumbism and Sideroblastic anemia.

Answer 52

Pappenheimer bodies or Siderocytic granules

Question 53

With one blunt pointed and protruding end hence appears as “Washington movement shaped” or “finger like projection”.

Answer 53

Hgb SC