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Hematology > WBC Anomalies/Abnormalities > Flashcards

WBC Anomalies/Abnormalities Flashcards

1
Q

The stain used to identify Downey cell.

A

Pyronine stain (red)

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2
Q

An abnormal reactive lymphocyte or virucyte with large cytoplasm than nucleus. Has pseudolobilations.

A

Downey cells

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3
Q

Related to Kissing disease or Acute IM and EBV.

A

Downey cells

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4
Q

A monocyte with a phagocytosed nucleus of a lymphocyte.

A

Tart cells

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5
Q

Tart cells are present in patients with?

A

Drug sensitivity

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6
Q

The affected organ of LE cells.

A

Kidney

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7
Q

The disease present having the LE cells.

A

Lupus erythematosus (autoimmune disease)

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8
Q

A phagocytic neutrophil with phagocytosed degenerative nuclear mass off another neutrophil.

A

L.E. Cells

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9
Q

Ferrata cell is associated with what disease?

A

Subacute bacterial endocarditis (SBE)

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10
Q

A abnormal lymphocyte with segmented/lobulated nucleus.

A

Rieder Cells

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11
Q

This disease is observed in Rieder cell abnormality.

A

Chronic Lymphocytic Leukemia (CLL)

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12
Q

A thin, thread like structure arising from the nucleus associated with Malignant abnormal changes.

A

Hairy Cell

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13
Q

Stain used to identify Hairy cell leukemia.

A

TRAP

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14
Q

Similar to plasma cell, except of no cartwheel chromatin pattern.

A

Turk irritation cell

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15
Q

Presence of 2 nucleus found in one cell.

A

Tuinning deformity

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16
Q

Associated disease in Tuinning deformity.

A

Pernicious anemia

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17
Q

Hyposegmentation described as “Pince-nez” or “Dumbbell shaped”.

A

Pelger-huet Anomaly

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18
Q

Pince-nez is a congenital failure that can be seen in leukemia on what kind of cell?

A

Neutrophil

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19
Q

A blue colored inclusions seen in cytoplasm having large vacuole.

A

Dohle Amato bodies

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20
Q

Thought to be remnants of Rough ER using Giemsa stain.

A

Dohle Amato Bodies

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21
Q

Dohle Inclusion is present with patients having?

A

Toxic conditions, severe infections, burns and Chemotherapy

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22
Q

Associated with Dwarfism or Gargoylism or Pfaunder hurler syndrome.

A

Alder Reilly Bodies

23
Q

Coarse azurophilic granules seen in granulocytes most commonly in neutrophils. Inherited as recessive trait.

A

Alder Reilly Bodies

24
Q

A sex chromatin of somatic cell (X-chromosome).

A

Barr Bodies

25
Q

A knob like structure arising from the lobe of neutrophil. Exclusive to females “Sexing of PMN”.

A

Drum stick

26
Q

Jordan’s Anomaly is commonly found in patients with?

A

Muscular dystrophy

27
Q

A fat containing granule observed in granulocyte and monocyte.

A

Jordan’s Anomaly

28
Q

Similar to Dohle bodies but usually seen with Giant platelets.

A

May Hegglin Anomaly

29
Q

Characterized by the presence of Peroxidase + Dohle like bodies.

A

Chediak higashi syndrome

30
Q

Stains used to identify Czediak Higashi Syndrome.

A

Sudan black B, Acid phosphatase, and Peroxidase +

31
Q

Auer Rod is usually seen with patients having this disease.

A

Acute monocytic/myelocytic Leukemia

32
Q

A rod like structure seen in cytoplasm of monoblast and myeloblast.

A

Auer bodies or Auer Rod

33
Q

Platelets encricling the peripheral borders of neutrophil.

A

Platelet Satellitosis

34
Q

An abnormal neutrophil with 5-10 lobes seen mostly in Pernicious Anemia(Macrocytic normochromic).

A

Hypersegmented Neutrophil

35
Q

Thorn cell, Spur cell with 5-10 irreversible thorn like projections.

A

Acanthocytes

36
Q

Disease associated in Acanthocytes.

A

Hemolyic anemia, Alcoholic cirrhosis, and abetalipoproteinemia

37
Q

Reversible thorn like projections that increase when BUN increase.

A

Burr cell

38
Q

Occur in RBC placed under hypertonic NaCl solution.

A

Echinocyte or Crenated RBC

39
Q

Sausage shaped found in Pernicious Anemia or Hereditary Elliptocytosis.

A

Elliptocytes

40
Q

With thin peripheral cell membrane found in Microangiopathic H.A.

A

Keratocyte or Blister cell

41
Q

Round cells lacking central pallor related with Hereditary spherocytosis and Spectrin deficiency.

A

Spherocytes

42
Q

Slitlike central area of palor seen in Alcoholism and Rh null disease.

A

Stomatocytes or Mouth cell

43
Q

Helmet shaped. Fragmenting RBC, found in HA, severe burns, diffuse intravascular coagulation syndrome (DIC).

A

Schistocyte

44
Q

Tear drop cell typically observed thalassemia, Myelofibrosis, and Pernicious anemia.

A

Dacrocyte

45
Q

Similar to tear drop but with long tail.

A

Racket cell

46
Q

Also known as codocyte, mexican hat cell , platycytes, leptocyte , Greek helmet cell , bull’s eye cell. Comes from the greek word “Kodon=bell”.

A

Target cell

47
Q

A star like RBC seen in certain anemias.

A

Astrocytes or Stellar cell

48
Q

Thin thread like structure in loop shape or figure of 8. Remnants of nuclear membrane (mitotic spindle).

A

Cabot rings

49
Q

Observed in patients with Pernicious anemia and Lead poisoning. Stains reddish purple with wright’s stain.

A

Cabot rings

50
Q

A small round darkly staining body, remnants of the nucleus seen in HA, PA and after splenectomy. (DNA)

A

Howell-Jolly bodies

51
Q

A fine or coarse basophilic stipplings (ribosome) seen in RBC that normally loss upon cell maturation.Seen in Lead poisoning.

A

Basophilic Stippling

52
Q

Non-heme iron deposits found in the RBC, usually Prussian blue positive. Seen in Plumbism and Sideroblastic anemia.

A

Pappenheimer bodies or Siderocytic granules

53
Q

With one blunt pointed and protruding end hence appears as “Washington movement shaped” or “finger like projection”.

A

Hgb SC

Hematology (5 decks)

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