Erythropoiesis

Question 1

Size of the Rubriblast cell.

Answer 1

14-20um

Question 2

Cytoplasm is deeply basophilc. Nucleus is relatively large, round or slightly oval.

Answer 2

Rubriblast or Pronormoblast or Proerythroblast

Question 3

Has a size of 12-17um and the hemoglobin synthesis starts.

Answer 3

Prorubricyte or Basophilic normoblast

Question 4

Cytoplasm is intensely basophilic. Nucleus is relatively large, round or slightly oval, nucleoli are not usually visible. NC ratio of 6:1.

Answer 4

Prorubricyte or Basophilic normoblast

Question 5

10-15 um, blue-gray to pink gray, with large range in color due to start of hemoglobin production, round nucleus. NC ratio of 4:1.

Answer 5

Rubricyte or Polychromatophilic normoblast

Question 6

7-12 um,pinker because of increased hgb production. Nucleus is small, pyknotic nucleus (partially extruded from cell). NC ratio of 1:2 and the last to contain nucleus.

Answer 6

Metarubricyte or Orthochromic normoblast or Acidophilic normoblast

Question 7

7-10 um, pink to slight pinkish gray, with fine basophilic reticulum of RNA. Stains only with supravital stains (NMB, BCB).

Answer 7

Retics or Reticulocyte or Polychromatophilic erythrocyte

Question 8

6.2-8.2 um, pink in color and last stage of erythropoiesis.

Answer 8

Mature erythrocyte or RBC

Question 9

NC ratio of Rubriblast/Pronormoblast

Answer 9

8:1 with 1-2nucleoli

Question 10

Start of hemoglobin production and last to undergo mitosis. Polychromasia is evident.

Answer 10

Rubricyte or Polychromatophilic normoblast