Water Balance 3, 4, 5 Flashcards

1
Q
Which of the following ions is abundantly present in the ICF?
A. Bicarbonate
B. Sodium
C. Chloride
D. Phosphate
A

Phosphate

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2
Q

Concerning body fluid compartments which of the following is true?
A. Transcellular water is located in the spaces b/w cells
B. ECF consists of interstitial fluid, plasma and transcellular water
C. Glomerular filtrate is an interstitial fluid

A

ECF consists of interstitial fluid, plasma and transcellular water

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3
Q

T/F: One important stimulus for thirst is increased ECF osmolality.

A

True

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4
Q

T/F: The major force favoring filtration at the arterial end of capillaries is the hydrostatic pressure of the blood.

A

True

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5
Q

T/F: An edema is an accumulation of water in the interstitium.

A

True

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6
Q

T/F: All of the homeostatic mechanisms that monitor and adjust the composition of body fluids responds to changes in the ECF, not in the ICF.

A

True

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7
Q

Homeostatic adjustments occur in response to changes in what?

A

Plasma volume or osmolality (total concentration of solutes).

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8
Q

Can receptors detect how much water, sodium, chloride, or potassium is present in the entire body?

A

No

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9
Q

T/F: Cells are able to move water molecules by active transport.

A

False, all water movement across cell membranes occur passively, in response to osmotic
gradients.

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10
Q

When will the body content of water or electrolytes rise?

A

If intake exceeds outflow and fall if losses exceed gains.

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11
Q

What are physiological adjustments regulated by?

A

Circulating hormones

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12
Q

Why are ICF and ECF often called fluid compartments?

A

They behave as distinct entities

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13
Q

What is calcium required for?

A

Strong bones and teeth

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14
Q

What is chloride necessary for?

A

In the stomach to create HCl

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15
Q

What is potassium required for?

A

Regulates water and electrolyte content of ICF

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16
Q

What is sodium required for?

A

Controls body water distribution between ECF and ICF

17
Q

How are compartment volumes are measured by?

A

Determining the volume of distribution of a tracer substance

18
Q

A tracer should be…?

A

Non toxic, not metabolized, rapidly & evenly distributed, not be excreted, easy to measure, not interfere with body fluid distribution

19
Q

What is the difference b/w ionic tracers and crystalloid tracers?

A

The ionic tracers are small and distribute throughout the ECF & there is some entry into cells. The crystalloids are larger and less diffusable throughout the ECF.

20
Q

Tracer substances used to measure body fluid compartments must be…
A. Nontoxic
B. Metabolized
C. Rapidly & evenly distributed in the compartment
D. A & B
E. A & C

A

Nontoxic and Rapidly & evenly distributed in the compartment

21
Q

What are the properties of indicator substances used to calculate GFR?

A

They must be freely filterable
Their filtered amount must not change due to resorption or secretion in the tubule
They must not be metabolized in the kidney
They must not alter renal function

22
Q

What are the two commonly used indicator substances?

A

Inulin and creatinine

23
Q

What is GFR also called, and what is the definition?

A

Clearance = the rate the plasma is cleared of a substance, if the substance freely filterable

24
Q
Which of the following hormones are involved in water balance?
A. ADH
B. Aldosterone
C. ANP
D. A & B
E. All of the above
A

All of the above

25
When there is a water deficit, what happens to the osmolarity?
Increases
26
When there is a water excess, what happens to the osmolarity?
Decreases
27
T/F: Diabetes insipidus occurs when the kidneys cannot concentrate the urine normally, and a large amount of dilute urine is excreted.
True
28
What happens with diabetes insipidus centralis?
Lack of ADH synthesis in the posterior pituitary, causes tumors and hypothalamus damage
29
What happens with diabetes insipidus renalis?
ADH is produced but can't act in the kidneys, causing kidney disease
30
What is the difference between hypovolemia and dehydration?
Hypovolemia is loss of fluid volume, versus dehydration is reduced fluid volume
31
What is intracellular edema?
Intracellular swelling
32
What are some causes of intracellular edema?
Hyponatremia, ischemia, inflammation
33
What is extracellular edema?
Excess fluid in extracellular space
34
What are some causes of extracellular edema?
Increased capillary pressure, decreased plasma | proteins, increased capillary permeability, blockage of lymph return
35
T/F: A lymph edema is a kind of intracellular edema.
False