Walfrin (Case Study)

Question 1

How does Warfarin “Work”

Answer 1

inhibits enzyme that reduces oxidised Vitamin K

Cant participate in prothrombin activation.

Question 2

Clotting factors mechanism

Answer 2

1. activation of prothrombin
2. carboxylase
3. Vitamin K is cofactor
4. oxidised Vitamin K
5. Warfarin inhibits reduction.

Question 3

Foods to avoid on Warfarin and WHY

Answer 3

Vitamin K food constituants = Kale, spinach
GREEN LEAFY VEG

Provide plenty of reduced vitamin K which will continue producing prothrombin = clotting factor.

Question 4

2 supplements to avoid on Warfarin

Answer 4

Vitamin K

Vitamin E - reduced production clotting factor prothrombin and thin blood even more.