W4 D2 - Adrenal Insufficiency

Question 1

Describe the function of the adrenal glands

Answer 1

Cortisol
* anti-inflammatory properties, suppresses immune system
* increases serum glucose levels
* potentiates sympathomimetics

Epinephrine
Norepinephrine
Aldosterone
Testosterone

Question 2

Describe Critical Illness-Related Corticosteroid Insufficiency (CIRCI) and patients at risk, diagnosis., & treatment.

Answer 2

patients at risk
* septic shock
* moderate/severe ARDS
* long term critical illness
* previous glucocorticoid use
* brain injury/ intracranial hypertension
* systemic inflammatory response

diagnosis

treatment

Question 3

What are some manifestations of CIRCI?

Answer 3

• hypotension without known cause
• cannot be titrated off vasopressors
• persistent inflammation
• hypoglycemia
• low WBC