W11 Schizophrenia Spectrum Disorders Flashcards
What are the main symptoms of psychosis?
Disorganized symptoms, negative symptoms, positive symptoms.
What are disorganized symptoms?
Disorganized speech (e.g., derailment), inappropriate affect, disorganized behavior (e.g., psychomotor agitation, catatonia).
What are negative symptoms?
Avolition (lack of motivation), anhedonia (loss of pleasure), asociality (lack of interest in social interactions), alogia (poverty of speech), affective flattening (blunted emotional expression).
What are positive symptoms?
Hallucinations (perceptions without sensory stimulation) and delusions (strange beliefs despite contrary evidence).
What types of hallucinations are common in schizophrenia?
Auditory (79.8%), visual (30.7%), somatic/tactile (19.3%), olfactory (9.6%).
What are examples of delusions?
Persecutory, grandiose, religious, somatic, reference, command, mind reading, thought broadcasting, thought insertion, thought withdrawal.
What is the motivational view of delusions?
Delusions may be an attempt to find meaning in distressing experiences.
What is the deficit view of delusions?
Delusions may result from dysfunctional brain activation due to neurotransmitter imbalances.
What are the diagnostic criteria for schizophrenia?
At least two of the following: delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior, negative symptoms.
How long must symptoms persist for a diagnosis of Schizophreniform Disorder?
Symptoms must last at least 1 month but less than 6 months.
What distinguishes Schizoaffective Disorder from mood disorders with psychotic features?
In Schizoaffective Disorder, psychotic features are present for at least 2 weeks in the absence of mood episodes.
What environmental factors may increase the risk of schizophrenia?
Prenatal viral exposure, birth complications, urban living, minority stress, substance use.
What is the heritability estimate for schizophrenia?
Approximately 80%.
What role do neurotransmitters play in schizophrenia?
Dopamine and glutamate are implicated in symptom development and brain functioning.
What is the first-line treatment for schizophrenia?
Medication, typically neuroleptics/antipsychotics that are primarily dopamine antagonists.