Vulvar/Vaginal Cancer Flashcards
Risk factors for xINs
multiple sexual partners
sex at an early age
high risk HPV strains
Classic presentation of VIN
itching and irritation = fungal infection that wont resolve with anti-fungal cream
Treatment for VIN (unifocal vs multifocal)
unifocal = local excision multifocal = vulvectomy ot laser ablation
Classic presention of vulvar SCC
itching, pain, bleeding ulceration
size of lesion that leads to radical vulvectomy
> 2cm
what is verrucous carcinoma
well differentiated subtype of vuvlar SCC and has a good prognosis
50-90% of VAIN is assc with __ and __
VIN and CIN
Presentation of VAIN
usually asmx, but can have vaginal discharge or postcoital spotting
**CLASSIC: persistently abnormal pap but nml cervical bx
treatment/management of VAIN
colpo-directed bx –> local excision, laser ablation or topical 5-FU
Where is vaginal SCC typically found
upper 1/3 and posterior wall
red/superficial ulcer, precursor to clear cell adenocarcinoma
vaginal adenosis
how old are women that get vaginal clear cell carcinoma 2/2 to DES exposure
< 20 yo
red, velvety lesions + scarred white plaques
paget’s disease
20% of paget’s disease is assc with underlying ___
adenocarcinoma
PAS+, muclcamine +, alclan blue+
paget “halo” cells
