GYN- Mentrual Cycle Flashcards
what is thelarche?
breast development
what is pubarche?
growth of pubic/axillary hair
what is menarche?
onset of menses
hoow soon after thelarche is menarche?
~ 2.5 yrs
What is the age/timing of puberty?
"Always Go (to) The Pub, Men" 7 yo: adrenarch 8: gonadarche 9-- 10: thelarche 11: pubarche/Peak growth 12: menarche
what are the tanner stages
1: kid
2: buds
3: elevation
4: areolar mound (big nipples)
5: adult
what endo things can cuase infertility
hypothyroidism (inc TRH/TSH inc PRL which dec GnRH) hyper PRL (dec GnRH)
what is Kallman syndrome
congenital dec GnRH
at what point in menstrual cycle is E at peak?
end of follicualr phase/right before LH surge
smaller inc in middle of proliferative phase
what hormone is relatively constant during menstual cycle?
FSH, small bump with inc E
What do theca cells respond to/make/do?
stimulated by LH to make androgens (inc desmolase activity to convert cholesterol to androgens)
What do granulose calls respond to/make/do?
stimulatef by FSH to inc activity of aromatase which converts androgens to estrogens
when is woman in menopause
no menses > 12 mos
avg age for onset of menopause
51
how to diagnose menopause
elevated FSH
how to treat menopause + why treat?
lowest dose HRT (E and P) for only 6-12 mos
prevents osteoporosis, relif of smx
risks and CI to HRT
risks: inc endometrial hyperplasia/cancer
CI: clotting disorders, liver dz, pregnancy, E dept neoplasm (breast and endometrial cancer), undiagnosed vaginal bleedign (endometial ca needs to be r/o)