Vulva (Pathoma)

Question 1

What type of epithelium lines the vulva?

Answer 1

Keratinized Stratifies Squamous epithelium

Question 2

Bartholin Cyst- Definition, population, complication

Answer 2

Due to obstruction and inflammation of Bartholin duct

Question 3

Bartholin cyst presentation

Answer 3

Unilateral painful cystic lesion

Question 4

Condyloma

Answer 4

Warty squamous cell neoplasm of vulva due to HPV 6 or 11

Question 5

Condyloma histology findings

Answer 5

Koilocytic change. Rarely progresses to cancer

Question 6

What conditions can cause koilocytic change?

Answer 6

Condyloma and intraepithelial neoplasia

Question 7

Lichen sclerosis

Answer 7

Thinning of epidermis and fibrosis of dermis
Leukoplakia (white patchy thin skin)
Seen in postmenopausal women

Question 8

What is lichen sclerosis a risk factor for?

Answer 8

Squamous cell carcinoma of the vulva

Question 9

Lichen simplex chronicus

Answer 9

Benign thickening of vulvar squamous cell epithelium (hyperplasia)
Leukoplakia + thick, leathery vulvar skin
Symptoms: Chronic irritation and scratching

Question 10

Vulvar carcinoma

Answer 10

Presents as leukoplakia

Question 11

What re the two types of vulvar carcinoma?`

Answer 11

HPV-related: VIN, age 40-50

Non-HPV related: Hx of L.sclerosis, postmenopausal (Age>70)

Question 12

Extramammary Paget disease

Answer 12

Malignant vulvae epithelial cells

Erythematous pruritic ulcerated skin

Question 13

Is Extramammary Paget disease an indication of an underlying carcinoma?

Answer 13

No. No underlying cancer.