Vagina (Pathoma)

Question 1

Adenosis- Definition and RF

Answer 1

Persistence of columnar epithelium in upper 1/3 of vagina

RF: DES exposure in utero

Question 2

Clear cell adenocarcinoma

Answer 2

Malignant proliferation of glands with clear cytoplasm

Rare complication of DES-associated adenosis

Question 3

Embryonal Rhabdomyosarcoma
(Sarcoma butyroides)

Answer 3

Malignant tumor of immature skeletal muscle
Pres: grape-like mass from vagina or penis, bleeding
Age:

Question 4

Rhabdomyoblast xtic

Answer 4

Has cytoplasmic cross-striations

Positive for desmin and myoglobin

Question 5

Vaginal carcinoma casue

Answer 5

Usually high risk-HPV

From squamous epithelium of vaginal mucosa

Question 6

Vaginal carcinoma precursor

Answer 6

Vaginal intraepithelial neoplasia (VAIN)

Question 7

Mode of regional lymph node spread from vagina

Answer 7

Lower 2/3- To inguinal lymph nodes

Upper 1/3- To regional iliac nodes

Question 8

Typical causes of vaginitis

Answer 8

Gardnerella and syphilis

Question 9

Atrophic vaginitis

Answer 9

Thinning of vaginal lining due to lack of estrogen