Voluntary Motion And Basal Ganglia - 4/26 Karius Flashcards

1
Q

Information from VIP goes to where?

Fx?

A

F4

Creates a detailed map of the space around you (excited by proximity)

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2
Q

What does the superior parietal cortex do?

A

Provides information about where you are in space

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3
Q

Input from superior parietal cortex goes where?

Fx?

A

F2

Map of where your arm is in relationship to your body and the things around you

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4
Q

The anterior intraparietal area and PFG contains neurons that respond to?

A

Seeing an object to grasp (visually Dom)
Grapsing an object (motor Dom)
Either condition (visuomotor neurons)

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5
Q

The anterior intraparietal area and PFG relay their info to where?

A

F5

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6
Q

What do the F5 neurons fire with?

A

The goal NOT the motor act

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7
Q

The Premotor cortex receives sensory info from where?

Fx?

A

F4 and F5 - the ventral parts

IDs the intent of the motion and decides what motion to produce

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8
Q

The dorsal part of the Premotor cortex does what?

A

Applies the rules that determine whether it is appropriate to move

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9
Q

The supplementary motor area (SMA) is responsible for what?

Pre-SMA responsible for what?

A

Postural control

Plans the motor program required to make the action occur

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10
Q

Fx of the supplementary motor cortex?

A

Organize motor sequences and acquire motor skills

Executive control (switch strategies)

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11
Q

Give 3 characteristics about the primary motor cortex

A

Precentral gyrus
Controls specific movements
Arranged in columns

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12
Q

What layer of the primary motor cortex receives sensory input (Muscle and joint proprio)?

A

Layer 4

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13
Q

What layer becomes the output for the corticospinal (pyramidal) pathway?

A

Layer 5

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14
Q

What are the 2 kinds of columns?

A

On/off for agonist muscle

Off/on for the antagonist muscle

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15
Q

What are the roles of the cerebellum?

A

Sequence complex actions
Correct force/direction
Balance and eye movements
Learning of complex actions

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16
Q

Where is the spinocerebellum located?

Fx?

A

Centrally on either side of the vermis

Central - postural control
Either side - Force and direction

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17
Q

Where is the cerebrocerebellum located?

Fx?

A

Lateral regions

Plan complex motions
Sequence

18
Q

Whereas the vestibulocerebellum?

Fx?

A

bottom

Balance/eye movements that are PLANNED (future)

19
Q

Outputs from cerebellum are via where?

A

Deep cerebellar nuclei

20
Q

What is the sensory info to the vermis of the spinocerebellum?

Outputs to where?

A

Vestibular, auditory, and efferent copy

FIR
Fastigial n, Interpositus n., to rubrospinal tract

21
Q

The lateral part of the spinocerebellum controls what?

Also what?

A

Force and direction

Ballistic motions

22
Q

Inputs to lateral parts of spinocerebellum?

Outputs?

A

Muscle afferent and efferent copy

Interpositus n. To rubrospinal tract

23
Q

Cerebrocerebellum controls what?

Inputs from where?

Outputs to where?

A

Complex motions and sequencing of rapid movements

Cereberal cortex

Dentate n. Back to cortex

24
Q

Input to vestibulocerebellum?

Outputs?

A

Vestibular apparatus (Direct or indirect)

Fastigial n. To vestibular n.
Can ascend or descend

25
Q

What part of the brain creates a rough map of the space around you?

A

VIP (ventral intra parietal area)

26
Q

Basal ganglia are involved in what?

A

Planning and programming of movement

Initiation of movement

27
Q

What makes up the striatum?

Receives what?

A

Putamen and caudate nucleus

Inputs to the basal ganglia

28
Q

From the nigrostriatal dopaminergic system where is input coming from?

Going to where?

Effects?

A

SNPC

Nuclei to striatum

D1(+) and D2(-)

29
Q

The intrastriatal cholinergic system is between what?

Release what?

Effect?

A

Nuclei of the striatum

ACh

Excitatory

30
Q

The Striatonigral GABA-ergic pathway is from where to where?

Aka?

Leads to what?

A

From striatum to the SNPR and GPi

Direct pathway

Initiation of movement

31
Q

Information leaves the basal ganglia via what?

A

SNPR and GPi

32
Q

Where do the SNPR and GPi project to?

Release what?

A

Thalamus

GABA

33
Q

Where does the striatum receive inputs from?

A

Cortex via corticostriate tract (EAA)

34
Q

What pathway is tonically active?

What nt?

A

Nigrostriatal from SNPC

DA

35
Q

In which pathway is the SNPR and GPi inhibited?

What is released?

End result?

A

Direct

Less GABA in the thalamus

Thalamus excites cortex, initiates movement

36
Q

With activation of the indirect pathway there is more what?

What is inhibited?

A

Excitation of SNPR and GPi and more GABA released in the thalamus

Thalamus is inhibited

37
Q

In the indirect pathway, where do striatal neurons synapse?

What happens?

A

GPe

Release more GABA and activity in GPe is DEC

38
Q

Where do GPe neurons synapse?

Since GPe neurons are less active what happens?

A

Subthalamic nucleus

LESS inhibition of subthalamic nucleus (uses EAA)

39
Q

Where do neurons from the subthalamic nucleus synapse?

What happens when they are more active?

A

SNPR

More EAA released

40
Q

What does the SNPR and GPi do when over-activated?

A

Release more GABA and inhibits the thalamus

Therefore no motion

41
Q

2 major fx of association cortex?

A

Planning of complex motor actions

Carrying out thought processes