Vitamins Water Soluble

Question 1

Water soluble B vitamines

- significance?

Answer 1

Thiamin (B1)
Riboflavin (B2)
Niacin (B3)
- E releasing vitamins
- all are involved in glycolysis/krebs cycle

Question 2

Where are these founds?
Thiamin
Riboflavin
Niacin

Answer 2

Thiamin: pork, legumes

Riboflavin: dairy, eggs, meats

Niacin: meat/poultry, tryptophan (precursor)

Question 3

Types of Thiamin (B1) deficiency

Answer 3

Beriberi: nervous + cardiovascular system

1. “Dry”
2. “Wet”
3. Wernicke-Korsakoff

Question 4

Dry Beri beri sx

Answer 4

peripheral neuropathy, weakness + atrophy

Foot drop

Question 5

Wet Beri Beri sx

Answer 5

edema, circulatory collapse, CHF

Question 6

Wernicke-Korsakoff sx

Answer 6

confusion
OPHTHALMOPLEGIA
Ataxia
memory loss

Question 7

Riboflavin (B2) deficiency findings

Answer 7

(due to low dairy, animal products)

Cheilosis (cracked lips)
Angular stomatitis (lesions on side of lips)

Question 8

Niacin (B3) deficiency who’s at risk

Answer 8

“Pellagra”

1. Nutritional/dietary restriction
   - cornmeal based diet
   - Food faddism/restriction (rice diet)
   - breastfed infant of deficient mother
2. Malabsorption syndrome
3. Alcoholism
4. Metabolic “shunting” –> increased 5’HT –> decreased Tryptophan

Question 9

Pellagra 4 D’s

Answer 9

1. Diarrhea
2. Dermatitis
   - “Casal’s necklace”
3. Dementia
   - confusion, dizzy, hallucination
4. Death

*Niacin B3 def.

Question 10

B complex vitamins

Answer 10

“hematopoietic”
Folate
VIt B12

Question 11

Sources of folic acid

Answer 11

“foliage” deep green veggies
OJ
Whole grains

Question 12

What type of vitamin def leads to macrocytic anemia (High MCV) + hypersegmented neutrophils?

Answer 12

Folate + VIt B12

Question 13

Which VIt is necessary for the conversion of homocysteine –> methionine?

Answer 13

B12 (cobalamin)

• very intimately related to folate
• problem for vegans

Question 14

Which vitamin has neurological disturbances

+ macrocytic anemia and hypersegmented neutrophils

Answer 14

VIt B12
Neuro disurbances:
-depression, 
- paresthesias, 
- gait 
- disturbances, 
- burning tongue, 
- dizziness

Question 15

Fxns of Vit C (Ascorbic acid)

Answer 15

1. Reversible antioxidant, Vit E
2. Reducing equivalents to enzymes
3. Leukocyte fxn (increase WBC)
4. Cosubstrate in hydroxylation
   - collagen synth
5. Conversion of DA –> NE

Question 16

Which vitamins involve skin findings?

Answer 16

Niacin
Vit C
\_\_\_\_\_\_
(A)
K

Question 17

Which vit involve mouth findings?

Answer 17

Ribo
Vit C
Folate
B12
\_\_\_\_\_

Question 18

Which vit involve neuro findings?

Answer 18

Thiamin
(C)
B12
\_\_\_\_\_
E

Question 19

Which Vitamins involve anemia?

Answer 19

Vit C
Folate
B12
\_\_\_\_\_
E
(K)

Question 20

Which Vitamins present with these “other” sx?

-CHF

Answer 20

Thiamin

Question 21

Which Vitamins present with these “other” sx?

- eyes

Answer 21

Riboflavin

Question 22

Which Vitamins present with these “other” sx?

- Diarrhea

Answer 22

Niacin

Question 23

Which Vitamins present with these “other” sx?

- Joint pain

Answer 23

Vit C

Question 24

Which Vitamins present with these “other” sx?

- eyes + bindness

Answer 24

Vit A

Question 25

Which Vitamins present with these “other” sx?

- Rickets

Answer 25

Vit D

Question 26

Which findings do Vit C def present with?

Answer 26

All of them
Skin
Mouth
Neuro
Anemia
Joint pain