Adult Obesity & Metabolic Syn Flashcards
BMI
Body weight [kg]
/
Height [m^2]
Nl waist circ
18.5-24.9
Overweight waist circ
25-29.9
Obese waist circ
I: 30.0-34.9
II: 35.0-39.9
III: >40
BMI less accurate in which groups
- what does it underestimate?
elderly
certain ethnic groups
large muscle mass
BMI underestimates degree of adiposity
*used in conjunction with abdominal adiposity distribution
Abdominal adiposity is an independent predictor of?
- # that should cause worry in women and men
DM
HTN
CAD
Dyslipidemia
*Used along with BMI to identify related complications
> 35 in women
40 in men
Proposed med of why abdominal obesity is bad
Release of FFA into the blood stream –> into liver, causing insulin resistance
- FFA from intra peritoneal fat
AA seem to have a protective effect against adiposity, how?
Less likely to have low HDL and high TG
Waist circumference cutoffs correlated with presence of CV risk factors were 5-6 cm greater in AA men then white men
waist circ. Cutoff
> 102cm in men
88cm in women
*asians have lower cutoff b4 risk of diabetes comes into play
~80
WHo has highest rates of obesity in US?
AA
- risk of diabetes, HTN
Risk of DM begins to increase at which BMI?
> 21-23
- 90% of indiv who develop DM2 have BMI of 23 or higher
Why is obesity a risk factor for post-menopausal breast cancer?
Adipose resevoir for Estrogen
- More E that women is exposed to in lifetime can increase her chance
Metabolic syndrome associated
- abdominal obesity
- Glucose intolerance/insulin R
- HTN
- Atherogenic Dyslipidemia
- Proinflammatory/Prothrombotic state
Must have 3 of the 5 cut offs
- abdominal obesity/waist circum.
- TG
- HDL
- BP
- Fasting Glucose
Waist CIrc. cut off
Waist circumference:
Men: >102 (>40 in)
Women: >88 (>35)
TG level cut off
TG: >150 mg/dL (meets criteria for dyslipidemia)