Vitamins D Flashcards
Vitamin D other names
Antirachitic vitamin
Cholecalciferol (vitamin D3 in animals)
Ergocalciferol
(vitamin D2; as D-fortified)
Calcitriol (active form in
kidney)
Calcidiol (active form in
liver)
Vitamin D Chemistry
Exists in two forms in foods:
cholecalciferol
and ergocalciferol,
and produced by
UV light to 7-
dehydrocholester
ol (metabolite of
cholesterol)
Vitamin D Function
- Promotes normal bone
and teeth formation - Regulates calcium and phosphorus homeostasis
- Gene regulation in
chromosomal transcription rate
1 IU of Vitamin D
is equivalent to
0.025 ug cholesterol
Calcium, phosphorus, and calcitonin
for their absorption to
Vitamin D metabolism
Vitamin K
in calcium-binding
proteins activated by
vitamin D
Deficiency of vitamin D
Rickets
Osteomalacia
Osteopenia
Rickets
are modeled on
soft and fragile bones, bowed legs, and body
deformation in chest, spine, and pelvis
Osteomalacia
is calcium
deficiency
Osteopenia
is loss of calcium
that causes reduced bone density
Vitamin D Toxicity
Hypervitaminosis D –
caused by calcification
of kidneys and lungs,
nausea, weight loss,
and polyuria
Food sources
- Fish liver oils
- Cod liver oils (richest)
- Butter
- Clams
- Oysters
- Eggs
- Sardines
- Vitamin D-fortified
dairy (milk, margarine)