PROTEIN Flashcards
Originated from a Greek word “proteios” meaning “to hold first place” or “is of prime importance”
- large complex organic compounds composed of amino acids as the building units linked together in peptide bonds
PROTEIN
1 g of Nitrogen
6.25 g protein
Proteins perform three (3) general
functions:
- Build and repair cells and tissues
(structural role) - Supply energy (fuel nutrient)
- 1 gram yields 4 kcal
- Regulate body processes (regulator
of physiologic processes)
building blocks of protein molecule and they serve as the “currency of protein nutrition and malnutrition.”
Amino Acids
“amino” comes from the basic
amino radical group “acid” comes the or carboxylic group and a distinctive side group (or side chain) are attached
-NH2
–COOH
one that the body cannot be
synthesized,
therefore; they must be supplied
in the diet.
ESSENTIAL AMINO ACID (EAA) OR
INDISPENSABLE AMINO ACID
ESSENTIAL AMINO ACID (EAA) OR
INDISPENSABLE AMINO ACID
P - Phenylalanine
V - Valine
T - Threonine
T - Tryptophan
I - Isoleucine
M - Methionine
H- Histidine
A - Arginine
L - Leucine
L - Lysine
arginine is an essential amino acid for optimal growth and development, and must
therefore be provided in the diet.
For young organisms
arginine is a conditionally essential amino acid, especially in such conditions as trauma, burn injury, small-bowel resection, and renal failure.
For adults
normally not essential but
become essential under certain
clinical conditions
must be supplied by the diet when
the need for these AAs exceeds
the body’s ability to produce them
SEMI-ESSENTIAL AMINO
ACID OR SEMI-INDISPENSABLE AMINO ACID
SEMI-ESSENTIAL AMINO
ACID OR SEMI-INDISPENSABLE AMINO ACID
Proline
Serine
Arginine
Tyrosine
Glycine
Cysteine
Taurine
not a dietary essential
can be synthesized by the body
from essential AA or from an
available source of nitrogen to
form the amino group and a
carbon skeleton composed of
fragments from CHO or fat to form
the rest of the structure of the
available if they are not available
in the diet
NON-ESSENTIAL AMINO ACID (NEAA) OR
DISPENSABLE AMINO ACID
NON-ESSENTIAL AMINO ACID (NEAA) OR
DISPENSABLE AMINO ACID
Alanine
Aspartate
Glutamine
Glutamate
yields only AA upon complete hydrolysis
ex: albumins, globulins, glutenins, gliadin
Simple Proteins
simple proteins combined with non-protein groups
ex:
nucleoprotein,
phosphoprotein, etc.
lipoprotein,
Compound Proteins
According to Chemical Structure
ex:
peptones, proteoses and peptides
formed in various stages of protein
digestion
Derived Proteins