vitamin in adulthood quick review table Flashcards
B1 (thiamin) RDA based on
1) amount needed to maintain transketolase activity within RBC (TPP)
2) without excess urinary excretion
B2 (riboflavin) RDA based on
1) RBC glutathione reductase activity coefficient (FAD is a cofactor for this enzyme)
2) concentration of riboflavin in RBC
3) urinary riboflavin
B3 (niacin) RDA based on
urinary excretion of metabolites
B6 ( pyridoxine ) RDA based on
maintenance of adequate blood 5’pyridoxine phosphate levels
folate RDA based on
RBC folate and blood homocystiene levels
B12 RDA based on
maintenance of hematological status and b12 blood values
biotin (B7) AI based on
population studies without signs of deficiency
Choline AI based on
the prevention of liver damage assessed by serum alanine aminotransferase activity
B5 ( pantothenic acid ) AI based on
adequate intake to replace urine excretion
tryptophan may be converted to?/
niacin
niacin expressed as
NEs
which vitamins are mg/d
B1, B2, B3,B5 (AI), B6, Choline (AI), vit C, vit E
which vitamins are ug/d
B12, folate, vit A, biotin(AI), vit K (AI)
vit C RDA based on
1) maintains near optimal neutrophil concentration 2) min urinary excretion
vit A RDA based on
based on the amount needed to maintain a body-pool size that will ensure adequate storage given a time period of low intake or stress
Vit D RDA based on
based on health benefits associated with vit D status ( increases with age over 70 )
vit E RDA based on
based on the correlation between H2H2 induced RBC lysis and blood a-tocoperol
- need to note that DRI is based on 2R sterioisoforms, in which the all race forms have 1/2 the activity of 2R
vit K AI based on
based on representative dietary data on healthy individuals
when figuring out choline RDA, liver damage is assessed by which enzyme
alanine aminotransferase
the difference in how B5 and B7 AI are assessed
B5 is based on amount needed to replace urinary excretion, while B7 is based on population studies of healthy individuals without signs of deficiency
commo marker for thiamine deficiency and why
the activity of trans-keto-lase. which is an enzyme in RBC that converts PPP back into glycolytic intermediates. Thiamine diphosphate (TPP) is required as a cofactor along with Mg+
how does choline play a role in the homocysteine pathway
along with 5-met-TH4-folate, adequate choline is needed to get converted to betaine which is used to regenerate methionine from homocysteine
