Vitamin B12 (cobalamin) Flashcards
List the properties of vitamin B12
6
Water soluble
Insoluble in fat
Heat stable up to 100 degrees Celsius
Destroyed by strong acids
Destroyed by alkalis
Destroyed by light
What destroys cobalamin (B12)
4
Temperatures above 100 degrees Celsius
Light
Alkalis
Strong acids
List some food sources of cobalamin (B12)
Offal Eggs Milk Meat Cheese Fish
List a source of cobalamin (B12) other than food sources
Vegans must take supplements or fortified foods such as soya milk as cobalamin is only found in animal sources
List the functions of cobalamin (B12)
4
Aids the metabolism of fatty acids to release energy
Aids the metabolism of folate/folic acid
Maintains the myelin sheath which speeds up nerve impulses
Aids the formation of red blood cells
List the effects of deficiency of cobalamin (B12)
Tiredness and irritability due to a lack of energy
Increased risk or neural tube defects in a foetus
Delayed nerve impulses
Pernicious anaemia
A lack of cobalamin (B12) results in delayed nerve impulses, describe this deficiency
Delayed nerve impulses as a result of a damaged myelin sheath causes cognitive impairments such as memory loss or slow mental response
A lack of cobalamin (B12) result in pernicious anaemia, describe this deficiency
Pernicious anaemia is caused by low levels of red blood cells which are needed to transport oxygen
What is the RI for children?
0.7-1 micrograms
What is the RI for adolescents and adults?
1.4 micrograms
What is the RI for pregnant women?
1.6 micrograms
What is the RI for lactating women?
1.9 micrograms