Vitamin B1

Question 1

What are three conditions that present from Thiamine B1 deficiency

Answer 1

BeriBeri disease
Wernicke’s encephalopathy

Question 2

What is the difference between wet and dry BeriBeri disease

Answer 2

Wet: pain, paresthesias, peripheral edema, peripheral neuritis, >3 month Vit B1 deficiency
Dry: symmetric peripheral neuropathy, affects mostly legs

Question 3

What is Wernicke’s encephalopathy

Answer 3

Horizontal nystagmus, weakness in extraoccular movements, cerebellar ataxia, mental impairment can progress to memory loss and psychosis

Question 4

Vitamin B1 (Thiamine) deficiency treatment plan

Answer 4

Thiamine 200mg IV TID until improvement of symptoms, then transition to 10mg QD po dosing
Always treat alcoholics to avoid lactic acidosis

Question 5

What are sources of Vitamin B1 (Thiamine)

Answer 5

Yeast, organ meat, pork, legumes, beef, whole grains, nuts

Question 6

What is the use of vitamin b1 thiamine?

Answer 6

Nerve conduction and energy generation