Vitamin A Flashcards

1
Q

What is vitamin A active as?

A

alcohol, aldehyde, acetate, palmitate, and acid

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2
Q

What does retinoic acid not fulfill the requirements for?

A

visual purple and reproduction

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3
Q

What is the most popular synthetic form?

A

vitamin A palmitate

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4
Q

Vitamin A occurs only in _____

A

animals (carotenoids in plants)

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5
Q

Where is the highest levels of vitamin A found in the body?

A

the liver
-fish liver oils are very high

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6
Q

Colostrum contains __________ A as other milk

A

10x as much

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7
Q

What improves absorption of vitamin A?

A

bile salts and dietary fat

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8
Q

Vitamin A formula

A

C20H30O (Retinol)

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9
Q

Plays a role in the __________

A

visual purple cycle

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10
Q

Maintenance of ________

A

normal epithelium (normal = columnar; deficiency = squamous)

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11
Q

Needed for normal ___________ function

A

bone (slow osteoblast differentiation if deficient)

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12
Q

Can cause ___________

A

nervous symptoms and blindness

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13
Q

What happens to cerebral spinal fluid pressure in vitamin A deficiency?

A

pressure increases

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14
Q

Necessary for normal ___________

A

reproduction

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15
Q

Vitamin deficiency causes

A

-reduced appetite
-night blindness
-xerophthalmia (dry eye condition)
-runny eyes of cattle and sheep (copious lacrimation)
-Dried up tear glands in chickens
-increased keratinization of epithelium
-increased respiratory problems
-vaginal/repro tract problems
-favors formation of kidney stones
-congenital malformations in certain soft tissues
-liver and kidney damage
-diarrhea
-testicular degeneration (reversible)

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16
Q

Hypervitaminosis (toxicity)

A

-skin thickening
-interference with bone development
-prolonged prothrombin time
-increased cerebrospinal fluid pressure (hydrocephalus)
-lowered plasma cholesterol
-resorption of fetus
-decreased appetite

17
Q

What is converted into vitamin A?

A

carotene that isn’t absorbed into the bloodstream

18
Q

Where is carotene converted into vitamin A?

A

intestinal wall

19
Q

Rats, goats, sheep, and pigs are known as __________ in terms of carotene

A

white fat species

20
Q

Cows and horses are known as ____________ in terms of carotene

A

yellow fat species (because plasma containing carotene may by stored in liver and fatty tissues)

21
Q

Where is vitamin A stored?

A

liver (70-93% of vitamin A found here)
-remainder is in fat deposits, kidneys, adrenals, and other organs

22
Q

What do liver stores act as?

A

a buffer against subsequent dietary inadequacies

23
Q

All-trans relative biopotency %

A

100

24
Q

13-cis relative biopotency %

A

75

25
Q

11-cis relative biopotency %

A

24

26
Q

9,13-di-cis relative biopotency %

A

24

27
Q

9-cis relative biopotency %

A

21

28
Q

11,13-di-cis relative biopotency %

A

15

29
Q

Sources of vitamin A

A

-fish oils
-egg yolk
-liver
-milk fat

30
Q

Sources of carotenes

A

high in green leafy plants
-decreases due to storage
-rain damage and oxidation of sun loses up to 80% during first 24 hours of curing

31
Q

General requirement of vitamin A

A

20-100 IU/kg BW (5x for poultry)

32
Q

What increases stability of vitamin A?

A

-coating with gelatin
-adding the antioxidant vit. E

33
Q

What destroys vitamin A?

A

-certain metals
-high temperatures