Visual loss and blindness Flashcards

1
Q

what can cause sudden visual loss

A

vascular aetiology (retinal artery/ vein occlusion), vitreous haemorrhage, retinal detachment, ARMD wet type, closed angle glaucoma, optic neuritis, stroke

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2
Q

what is the main blood supply to the eye

A

branches of the ophthalmic

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3
Q

what supplies the optic nerve head

A

posterior cilliary artery

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4
Q

what vessel supplies the retina

A

central retinal artery

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5
Q

occlusion of what vasculature can cause sudden visual loss

A
retinal circulation (retinal artery and vein) 
optic nerve circulation
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6
Q

what haemorrhage can cause sudden visual loss

A
abnormal vessels (DM, wet ARMD)
normal vessels (bridging a retinal tear)
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7
Q

what are the signs and symptoms of central retinal artery occlusion

A

sudden visual loss
painless

RAPD
pale oedematous retina, thread like retinal

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8
Q

why do oedematous retinal ganglions make the eye appear pale

A

as choroid blood vessels underneath that make the eye appear red are no longer visible

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9
Q

why doesnt the macula get paler when ganglion cells become odematous (in central retinal artery occlusion)

A

as macula doesnt have ganglion cells over it

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10
Q

what can cause central retinal artery occlusion

A

carotid artery disease

emboli from the heart (vegetations/ thrombus on heart valve)

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11
Q

what is branch retinal artery occlusion

A

only one branch affected so partial vision loss

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12
Q

how do you tell the vessels apart in a fundoscopy

A

lighter one is the artery

darker one is the vein

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13
Q

what is amaurosis fugaxyout

A

transient central retinal artery occlusion

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14
Q

what are the symptoms of amaurosis fugaxyout

A

transient painless visual loss
‘like a curtain coming down’
last about 5 mins with full recovery
nothing abnormal on examination

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15
Q

what should you do in amaurosis fugaxyout

A

urgent referral to stroke clinic

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16
Q

what is central retinal vein occlusion associated with

A
endothelial change (diabetes) 
abnormal blood flow (hypertension) 
hypercoaguable state (cancer)

(neighbouring artery may stiffen and occlude vein)

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17
Q

what are the symptoms of central retinal vein occlusion

A

sudden visual loss

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18
Q

what are the signs of central vein occlusion

A

retinal haemorrhages, dilates tortous veins, disc swelling and macular swelling, cotton wools spots

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19
Q

what are cotton wool spots

A

ischaemia- small infarcts of the nerve fibres

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20
Q

what are the differences in artery and vein occlusion

A

artery will cause oedema

vein will cause haemorrhages

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21
Q

what is ischaemic optic neuropathy

A

occlusion of optic nerve head circulation (posterior ciliary arteries)

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22
Q

what inflammatory condition can cause ischaemic optic neuropathy

A

giant cell arteritis - lumen of artery becomes occluded due to gross thickening of artery wall

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23
Q

what cells id GCA

A

multinucleated giant cells

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24
Q

what are the visual symptoms and signs of ischaemic optic neuropathy

A

sudden severe visual loss
irreversible blindness
swollen optic disc, pale

25
what can immediate treamtment of ischaemic optic neuropathy prevent
bilateral visual loss
26
what are the symptoms of GCA
``` headache (temporal) jaw claudication scalp tenderness (painful to comb hair) tender/enlarged scalp arteries amaurosis fugax (transient darkness) malaise ```
27
what is a vitreous haemorrhage
a haemorrhage that occurs in the vitreous cavity of the eye
28
what can cause an abnormal vessel haemorrhage
e.g. in retinal ischaemia in diabetes/ retinal vein occlusion new fragile (curly) blood vessels form which bleed easily
29
what are the signs and symptoms of vitreous haemorrhage
loss of vision floaters loss of red reflex may see haemorrhage on fundoscopy
30
what does the red reflex tell you
that the media is clear
31
what are the signs and symptoms of retinal detachment
painless loss of vision sudden onset of flashes/ floaters (mechanical separation of sensory retina from retinal pigment epithelium) may have RAPD may see tear on ophthalmoscopy
32
what causes ARMD
multifactoral- age, smoking, family history, poor nutrition
33
what are the types of ARMD
wet- sudden visual loss | dry- gradual
34
describe wet ARMD
new blood vessels grow under retina from pigment epithelium up through the choroid leakage causes build up of fluid/ blood and eventually scarring
35
what are the signs and symptoms of wet ARMD
rapid central visual loss distortion (metamorphosia) haemorrhage/ exudate eye pale due to oedema flecks in eye exudates from vessels
36
what is glaucoma
progressive optic neuropathy leads to optic nerve damage
37
what is the angle in glaucoma
angle between the iris and the cornea
38
what is the path of aqueous fluid
produced by the ciliary body, travels between the iris and lens into the trabecular meshwork
39
what causes closed angle glaucoma
aqueous humour encounters increased resistance through the iris/lens channel increased pressure gradient causes peripheral iris to bow forward, obstructing trabecular meshwork- increasing pressure
40
what are the signs and symptoms of closed angle glaucoma
acute (ophthalmic emergency) painful, red eye, sudden visual loss, headache, N&V red eye, cloudy cornea, dilated pupil
41
what is the treatment for closed angle glaucoma
lower IOP with drops/ oral medication to prevent blindness
42
what are the causes of gradual visual loss
cataract, ARMD (dry type), refractive error, glaucoma, diabetic retinopathy
43
what is cataracts
cloudiness of the lens- abnormal changes in lens proteins (crystallins) causes changes in their chemical and structural nature causing them to loose their transparency
44
what causes cataracts
age, congenital (intrauterine infection), traumatic, metabolic (diabetes- reductase glucose to sorbitol), drugs (steroids)
45
what are the different types of cataracts
nuclear posterior (subcapuslar) christmas tree (polychromatic) congenital
46
what are the symptoms of cataracts
gradual decline in vision (hazy/blurred) | glare
47
when is surgery done for cataracts
is patient is symptomatic
48
what is the commonest cause of blindness in western world in patients over 65
ARMD
49
what type of of ARMD do you get drusens in what are they?
dry type- they are bi products of pigment cells which build up and stop nutirents diffusing through the choroid- retina becomes atrophic
50
what are the signs and symptoms of dry type ARMD
gradual decline in vision central vision missing (scrotoma) drusen (yellow flakes) atrophic patches of retina
51
what is the treatment for dry type ARMD
none- vision aids
52
what is myopia
short sighted- image focused infront of the retina of the retina
53
what is hypermetropia
long sighted- image focused behind the retina
54
what is astigmatism
usually irregular corneal curvature
55
what is presbyopia
loss of accommodation with age
56
what is the treatment for refractive error
glasses
57
describe open angle glaucoma
Trabecular meshwork gets clogged up and doesn’t allow the fluid draining from the eye Pressure increases gradually
58
what are the signs and symptoms of open angle glaucoma
often none cupped disc visual field defect may/ not have raised IOP