Eye in Systemic Disease (neurological conditions) Flashcards
what are the main features of neuro-ophthalmic disease
eye movement defects- double vision
visual defects- visual acuity, field loss
what is the biggest cause of eye problems
microvascular disease
what is de-myelination
loss of myelin shealth from (optic) nerve making it inefficient
what are inter-nuclear ophthalmoplegia (INO)
lesion affects medial longitudinal fasciculus (MLF) (inter nuclear connections) resulting in cranial nerve 3 and 6 being unable to coordinate their signals
=when the patient’s gaze is directed away from the side of the lesion, the ipsilateral (adducting) eye will not adduct and the contralateral (abducting) eye demonstrates horizontal nystagmus
what are supra nuclear defects
when problem with occular motility arises from an area before the cranial nerves
what muscles are affected by a 6th nerve palsy
lateral rectus (inability to abduct eye)
what type of diplopia will someone with a 6th nerve palsy get
horizontal
what can cause a 6th nerve palsy
microvascular
raised ICP
tumour
congenital
why is the 6th cranial nerve susceptible to raised ICP
as comes up from bottom of brain stem over the petrous tip
what causes papilloedema
raised ICP
what nerve is affected by a fourth nerve palsy
superior oblique (in ability to look medially (intorsion) and down (deoression in adduction), with palsy eye will lift when look medially)
what nerve palsy do you get a head tilt in
trochlear (IV) nerve palsy as trying to lift head to match high eye
what are the actions of superior oblique muscle
intorsion (adduction)
depression in adduction
weak abduction
what can cause a IVth nerve palsy
congential decompensated (will have double vision)
microvascular
tumour
bilateral (closed head trauma)
what is a compensated nerve palsy
where brain is still able to fuse two fields of vision so wont have diplopia
what is the longest cranial nerve. why is this important
trochlear- 4th
comes out of posterior brain stem- susceptible to trauma
what muscles does the occulomotor nerve supply (III)
medial rectus inferior rectus superior rectus inferior oblique sphincter pupillae levator palpebrae superioris
what muscle palsy causes ptosis
levator palpaebrae superioris- CN III
what are the signs of a III nerve palsy
ocular position= down and out (lateral rectus and superior oblique only ones working)
droopy lid - ptosis
what can cause a III nerve palsy
microvascular tumour aneurysm (close to circle of willis) MS congenital
what can cause a PAINFUL third nerve palsy
aneurysm
what causes a PUPIL SPARING III nerve palsy
microvascular (as parasympathetics in III nerve on the outside- more likely to be affected by an aneurysm)
what are the key word causes of the three palsys
all caused by vasculopathic/ tumour
III= aneurysm IV= congenital/ trauma VI= cranial pressure
what can cause inter opthalmoplegia
MS, vascular, lots e.g. stroke