Viruses

Question 1

Name the (+)ss RNA viruses

Answer 1

Retrovirus
Togavirus
Flavivirus
Coronavirus
Hepevirus
Calicivirus
Picornovirus

Retro toga party, flavored Corona, hippy California pickles

Question 2

Name the only dsRNA virus

Answer 2

Reovirus

Question 3

Name the (-)ssRNA viruses and what special piece they need

Answer 3

Arenavirus - Always
Bunyavirus - Bring
Paramyxovirus - Polymerase
Orthomyxovirus - Or
Filovirus - Fail
Rhabdovirus - Replication

They need to bring their own RNA-dep-RNA-pol to get (+)RNA

Question 4

Name the DNA viruses

Answer 4

HHAPPPPy
Hepadna
Herpes
Adeno
Pox - only replication in the cytoplasm
Parvo - only ss
Papilloma
Polyoma

Question 5

General DNA virus characteristics and exceptions

Answer 5

dsDNA - except parvo (-)ss
Icosahedral - except pox (complex)
Replicate in the nucleus - except pox

Question 6

Herpesviruses Characteristics

Answer 6

Large dsDNA, linear, enveloped, icosahedral

Question 7

Name the Herpesviruses

Answer 7

HSV-1 - historically oral, encephalitis
HSV-2 - historically genital
VZV - chickenpox // shingles
EBV - mononucleosis
CMV - immunocompromised
HHV-6 - roseola
HHV-8 - Kaposi sarcoma

Question 8

Characterize and name the Hepadnavirus

Answer 8

partial dsDNA, circular, enveloped

Hepatitis B Virus

Question 9

Characterize the Adenovirus and Diseases

Answer 9

dsDNA, linear, non-enveloped

Causes: febrile pharyngitis, acute hemorrhagic cystitis, pneumonia, conjunctivitis

Question 10

Characterize the Parvovirus

Answer 10

(-)ssDNA (only one), linear, non-enveloped

B19 virus

Question 11

Diseases caused by the B19 virus

Answer 11

Parvovirus

aplastic crisis in sickle cell
‘slapped cheeks’ in kids - fifth disease
hydrops fetalis in utero (red cell destruction)
PRCA in adults

Question 12

Characterize the Papilloma Virus

Answer 12

dsDNA, circular, non-enveloped
HPV 6,11 - genital warts
HPV 16,18 - high risk for CIN / cervical canver

Question 13

Characterize the Poxvirus

Answer 13

dsDNA, linear, enveloped
largest DNA virus
Smallpox
Cowpox
Mulluscum Contagiosum

Question 14

Name the segmented viruses

Answer 14

All are RNA
BOAR
Bunya, Orthomyxo, Arena, Reo

Question 15

Characterize the Reoviruses

Answer 15

dsRNA (only), linear, segmented, non-enveloped, icosahedral
Coltivirus - Colorado Tick Fever (Arbo)
Rotavirus - severe diarrhea

Question 16

Characterize the Picornaviruses

Answer 16

(+)ssRNA, linear, non-enveloped, icosahedral
PERCH
Polio
Echo - meningitis
Rhino - common cold
Coxsackie - meningitis, hand/foot/mouth, myocarditis
Hep A - acute viral hepatitis

Question 17

Characterize the Hepevirus

Answer 17

(+)ssRNA, linear, non-enveloped, icosahedral

Hep E

Question 18

Characterize the Caliciviruses

Answer 18

(+)ssRNA, linear, non-enveloped, icosahedral

Norovirus - gastroenteritis

Question 19

Characterize the Flaviviruses

Answer 19

(+)ssRNA, linear, enveloped, icosahedral
Hep C
Yellow Fever - arbo
Dengue - arbo
St Louis - arbo
West Nile - arbo

Question 20

Characterize the Togavirus

Answer 20

(+)ssRNA, linear, enveloped, icosahedral
Rubella
Eastern/Western Equine Encephalitis - arbo

Question 21

Characterize the Retroviruses

Answer 21

(+)ssRNA, linear, enveloped
HTLV1 - Tcell leukemia, tropical spastic paralysis thingy
HIV
Bring a reversetranscriptase with them

Question 22

Characterize the Coronavirus

Answer 22

(+)ssRNA, linear, helical (only (+)RNA that’s helical), enveloped
Common cold, SARS

Question 23

Characterize the Orthomyxoviruses

Answer 23

(-)ssRNA, linear (8 segments), helical, enveloped

Influenza viruses