Stuff We Got Wrong That One Time Flashcards

1
Q

Best approach to somatic symptom disorder

A

Increase regular scheduled visits with primary care provider

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2
Q

Histology of bone in Hyperparathyroidism

A

Subperiosteal resorption with cystic degeneration

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3
Q

Ataxia Telangiectasia

A

Issue with Non-homologous end joining. Can see recurrent pulmonary infections, ataxia, nystagmus, superficial blanching nests of distended capillaries on sun exposed areas.

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4
Q

Class I anti-arrythmics affinity for receptor and quickest dissociations

A

Class IB has the lowest affinity, IA is second lowest, Class IC has the highest affinity (BAC)

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5
Q

Treatment for Severe SSRI overdose

A

Cyproheptadine

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6
Q

Why does PaO2 drop slightly between Pulmonary capillaries and Left atrium?

A

Contribution to blood volume by returning bronchial veins before the Left atrium

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7
Q

Hyperacute allograft rejection

A

Due to preformed antibodies. See arterial fibrinoid necrosis and capillary thrombosis leading to gross molting and cyanosis

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8
Q

Club cells in lungs

A

Function in detoxification of lungs through P450 mechanism.

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9
Q

NO functions in autoregulation of…

A

Larger arteries and pre-arteriolar vessels

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10
Q

Adenosine functions in autoregulation of…

A

Small coronary arterioles

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11
Q

How fast to cardiac myocytes stop contracting during ischemia?

A

Within 1 minute. Will continue anaerobic glycolysis and not die for 30 minutes.

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12
Q

Place in vasculature with lowest oxygen content

A

Coronary sinus- Heart extracts the most O2 from the blood.

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13
Q

Process of Acid Fast Staining

A

Stain with carbolfuchsin, use HCl and alcohol to wash off stain, counterstain with methylene blue

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14
Q

Cord factor in mycobacterial species

A

Seen by growth of ropelike cords in serpantine pattern on microscopy. Cord factor is a mycoside, presence correlates with virulence of bug. Inactivates PMNs, damages mitochondria, causes release of TNF

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15
Q

5-FU mechanism of action

A

Binds THF and thymidylate synthetase in stable confirmation, thus making TS unavailable for thymidine synthesis. Leucorvin (formyl-THF) actually increases efficacy of 5-FU.

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16
Q

Hawthorne effect

A

Observer effect. Tendency for study subjects to change behavior once they know they’re being studied.

17
Q

Indication of severity of mitral stenosis

A

Earlier Opening snap = worse. Low A2-OS interval