viruses Flashcards

0
Q

Acyclovir

A

stops replication of herpesviruses by interfering with viral DNA polymerase

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1
Q

Fuzeon

A

stops entry of HIV into cells

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2
Q

HAART

A

highly active anti-retroviral therapy, stops HIV replication

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3
Q

Tamiflucose

A

stops budding and release of influenza viruses from host cell

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4
Q

acute infection

A

short, where virus is replicates and produces many virons, most cells are killed

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5
Q

latent infection

A

virus persist in host cells, but doesn’t replicate (herpes virus)

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6
Q

Chronic infection

A

longer, where virus replicates without causing host cell lysis, ex: hep C

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7
Q

Chickenpox

A

acute- fever, itchy, rash
latent- doesn’t happen until triggered by external factors, then becomes shingles

Zoster is a reactivation of latent infection, begins as a local skin eruption close to dorsal root ganglia, has rash and pain

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8
Q

Varicella zoster virus (HHV-3), chickenpox and shingles

A

spread by airborne and direct routes, vesicles in both are infectious, incubation period of 14 days, can be transmitted during incubation period

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9
Q

Complication of chickenpox

A

main is post hepetic neuralgia infection

-CNS like meningitis, bacterial infection

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10
Q

treatment of chickenpox and shingles

A

antivirals such as acyclovir and analogus

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11
Q

oncogenic viruses

A

cancer cells, wart virus- benign. Cancer virus can be DNA or RNA

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12
Q

Burkitt’s lymphoma

A

herpesvirus, EBV

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13
Q

how are viral infections diagnosed?

A

cell cultures- it’s labor intensive and low

Fluorescent antibody stain- easy and virus turns green

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14
Q

difference between chickenpox and smallpox

A

chickenpox lesions are in different stages

smallpox are same stage of development

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15
Q

prions

A

misfolded protein disease, cause dysfunction. Ex include Scrapies, kuru, Mad cow disease

16
Q

DNA dependent DNA polymerase

A

where host is DNA virus, to make more virus DNA, happens in nucleus

17
Q

RNA dependent RNA polymerase

A

where virus carry its own polymerase enzyme to produce mRNA, happens in cytoplasm and carried by virus

18
Q

RNA dependent DNA polymerase

A

integrated viral DNA transcribed by host cell polymerase to make more virus mRNA