viruses

Question 0

Acyclovir

Answer 0

stops replication of herpesviruses by interfering with viral DNA polymerase

Question 1

Fuzeon

Answer 1

stops entry of HIV into cells

Question 2

HAART

Answer 2

highly active anti-retroviral therapy, stops HIV replication

Question 3

Tamiflucose

Answer 3

stops budding and release of influenza viruses from host cell

Question 4

acute infection

Answer 4

short, where virus is replicates and produces many virons, most cells are killed

Question 5

latent infection

Answer 5

virus persist in host cells, but doesn’t replicate (herpes virus)

Question 6

Chronic infection

Answer 6

longer, where virus replicates without causing host cell lysis, ex: hep C

Question 7

Chickenpox

Answer 7

acute- fever, itchy, rash
latent- doesn’t happen until triggered by external factors, then becomes shingles

Zoster is a reactivation of latent infection, begins as a local skin eruption close to dorsal root ganglia, has rash and pain

Question 8

Varicella zoster virus (HHV-3), chickenpox and shingles

Answer 8

spread by airborne and direct routes, vesicles in both are infectious, incubation period of 14 days, can be transmitted during incubation period

Question 9

Complication of chickenpox

Answer 9

main is post hepetic neuralgia infection

-CNS like meningitis, bacterial infection

Question 10

treatment of chickenpox and shingles

Answer 10

antivirals such as acyclovir and analogus

Question 11

oncogenic viruses

Answer 11

cancer cells, wart virus- benign. Cancer virus can be DNA or RNA

Question 12

Burkitt’s lymphoma

Answer 12

herpesvirus, EBV

Question 13

how are viral infections diagnosed?

Answer 13

cell cultures- it’s labor intensive and low

Fluorescent antibody stain- easy and virus turns green

Question 14

difference between chickenpox and smallpox

Answer 14

chickenpox lesions are in different stages

smallpox are same stage of development

Question 15

prions

Answer 15

misfolded protein disease, cause dysfunction. Ex include Scrapies, kuru, Mad cow disease

Question 16

DNA dependent DNA polymerase

Answer 16

where host is DNA virus, to make more virus DNA, happens in nucleus

Question 17

RNA dependent RNA polymerase

Answer 17

where virus carry its own polymerase enzyme to produce mRNA, happens in cytoplasm and carried by virus

Question 18

RNA dependent DNA polymerase

Answer 18

integrated viral DNA transcribed by host cell polymerase to make more virus mRNA