Virus's Flashcards
parvo thru orthomyxo
Full name of canine parvo?
Parvoviridae parvovirus CPV-2
Full name of human parvo? What does it cause?
Parvoviridae erthroparvirus HPV B19. Causes Fifth’s disase
Full name of human adenovirus?
Adenoviridae Mastadenovirus human mastadenovirus A-G
What nucleic acid does parvovirus us? what about shape and envelope?
ssDNA, non enveloped, icosahedral.
How did adenovirus get it’s name?
first isolated from adenoid tissue
What nucleic acid does adenovirus us? what about shape and envelope? (what is special about its shape)
non enveloped icosahedral. dsDNA linear. it has the fibril projections that are highly antigenic.
What is the full name of the causal agent of fifth’s disease
Parvoviridae erythroparvovirus Primate erythroparvovirus B19
Full name of Herpes (STD and cold sores)?
Herpesviridae Alphaherpesvirinae Simplexvirus herpes simples virus (HSV)
Full name of cytomegalovirus?
Herpesviridae betaherpesvirinae Cytomegalovirus human betaherpesvirus 5?
What nucleic acid does HSV us? what about shape and envelope?
dsDNA icosahedral, enveleope.
Full name of EBV?
Herpesvirinae Gammaherpesvirinae Lymphocrytovirus EBV
What nucleic acid does EBV us? what about shape and envelope?
Enveloped icosahedral with dsDNA.
Full name of causal agent for chickenpox.
Herpesvirinae Alphaherpesvirinae Varicellovirus VZV
What is the full name for the causal adgent of smallpox?
Poxviridae Orthopoxivirus Variola virus
What nucleic acid does smallpox use us? what about shape and envelope?
brick-shaped capsid with envelope. dsDNA
Full name of the causal agent of hepatitis A?
Picornaviridae Heptovirus Heptovirus A
Full name of the causal agent of hepatitis B?
Hepadnaviridae orthohepadnavirus Hep B virus
Full name of the causal agent of hepatitis C?
Flaviviridae Hepacicvirus Hepacivirus C
What nucleic acid does Hep A us? what about shape and envelope?
non-enveloped icosahedral with ssRNA
What nucleic acid does Hep B us? what about shape and envelope?
Enveloped icosahedral with dsDNA
What nucleic acid does Hep C us? what about shape and envelope?
enveloped icosahedral with ssRNA
Which of the hep’s are oncogenic, which are not?
Hep A: non oncogenic
Hep B and C: oncogenic
what is the name of the causal agent of poliovirus?
Picornaviridae Enterovirus Poliovirus
What is the cause of HFandM disease
Picornaviridae enterovirus coxsackievirus
What nucleic acid does polio use? what about shape and envelope?
ssRNA with nonenveloped icosahedral
What nucleic acid does HFandM use? what about shape and envelope?
nonenveloped icosahedral +ssRNA
What is the full name of the flu?
Orthomyxoviridae Influzavirus Influenza A-C
What nucleic acid does the flu use? what about shape and envelope?
-ssRNA with envelope, but pleomorphic shape
What are the three virulence factors of adenovirus?
-E1 regions disable tumor surpressor genes and stimulate cell into S phase
-E3 region encodes anti-imunity proteins
-enlargement of cells into grape like clusters
What are the virulence factor for herpes (4)
-Latent infection in neurons
-Spike glycoproteins interfere with immune response
-Viral host shutoff degrade host cell mRNA
-beta proteins degrade and marginate cell chromatin
What glycoprotein allows for differentation between HSV-1 and HSV-2
Glycoprotein G
What’s the treatment for alphaherpesvirius’s
acyclovir
What are the key virulence factors of influenza (3)?
Hemagglutinin (HA binds to sialic acid receptors), Neuraminidase (NA cleaves SA residues and allows for entry), Antigenic drift/shift
How to differenate HAV, HBV and HCV
Transmission: HAV is spread fecal-oral, HBV/HCV is spread via blood
Diagnosis: HAV is sero, HBV is IDed via HBsAg antigen test, HCV is tested via sero
Prevalence: HAV is common among poor children, HBV is common amoung hospital workers
What are the two major groups in the picornavirus family?
Enterovirus: polio and cocksakie
Rhinovirus:
What is the structure, nucleic acid and envelope of picornaviridae?
non-enveloped icosahedral with +ssRNA. cytoplasmic replication
Which virus causes crypt cells in intestinal epithelium?
Rotavirus
Full name of Rotavirus?
Reoviridae Sedoreviridae Rotavirus Rotavirus (A-E)
What is the full name of the Norwalk/norovirus?
Calciviridae Norovirus Norwalk vrus
What is the shape, envelope and nucleic acid of Calciviridae? What makes it shape special?
non-enveloped icosahedral. Has cup-like depressions on capsid like a socceer ball. ssRNA (+).
Family and genus of Zika, west nile and yellow fever virus
Flaviviridae, flavivirus
Full name of ebola virus?
Filoviridae ebolavirus Zaire ebolavirus
What is the causal adgent of venezuelan equine encephalits?
Togavirus in South america
What are the three types of diseases caused by arbovirus’s
Fever: West nile, Dengue fever
Encelphalitis: togavirus (VEE)
Hemorragic fever: ebola and zika