Final Flashcards
What is the morphology of paramyxovirusues
ssRNA with enveloped icosahedral
What are the two major subfamilies of Paramyxoviridae?
Rubelavirus and Morbillivirus
What diseases does the Rubelavirus subfamily have? how about the morbilllivirus?
Rubella: Mumps,
Morbilli: measles (rubeola)
secondary infection caused by measles? (3)
Pneumonia, ear aches, encephliaitis
What tissues does measles populate? what’s it’s route
Repriatory to lymph to diffuse. Likes to populate mucous membranes
Koplik spots are indicitvate of what disease?
Measles: white bumps at back of thr
What are the three virulence factors of measles?
P protein: neg regulates antiviral response (NF-kappa B)
V protein: blocks STAT activities
C protein: interferes with PKR
Where is meales predominatly
Africa and asia
What family and subfamily causes mumps
Paramyxoviridae Rubulavirus
What are the clinical symptoms of mumps (3)
swelling of parotid glands, spams, difficulty chewing, more severe past purperty
What is the route of entry for mumps?
URT thru the bloody into the glandular tissues
What is the family of rubella
Togaviridae Rubelavirus
What are the symptoms of Rubella (2), what is one of the key problems with diagnosis?
Symptoms are slight to not there and breif, but can pose significant pregnancy complications. Enlarged lymphnodes behind ear and back of neck, rash with light pink spots,
How does Rubella invade the body? (route)
resp to the blood to viremia (antibodies lead to rash and joint pain)
What is the morphology of coronaviridae
enveloped icosahedral with +RNA
