Virus de la Hepatitis B Flashcards

1
Q

Generalidades de Hepatitis B

A

Hepadnavirus
Codifica transcriptasa reversa
Virus envuelto

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2
Q

Antigenos de Hepatitis B y función

A

HBcAg: proteína adherida al genoma
HBsAg: glucoproteína de superficie
HBeAg: no se ensambla

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3
Q

En la hepatitis B que es lo que crea la inmunidad con la enfermedad

A

La glicoproteina de superficie que interactua con cel diana

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4
Q

Tasa de prevalencia de la hepatitis B

A

0.3- 1.4%

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5
Q

En quien, en donde y porque se da normalmente la hepatitis B

A

En hombres, en poblaciones indígenas. Por compartir agujas de las drogas

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6
Q

Vía de contagio de Hepatitis B

A

Sangre, sexual y vertical

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7
Q

Periodo de incubación de Hepatitis B

A

Prolongado. De 46-160 dias

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8
Q

Cuadro clínico por Hepatitis B

A

Infección sintomática
- Lactante: -5%
- menor de 5 años: 5-15%
-+ de 5 años: 33-50%
Ictericia dolor abdominal (sx inespecificos- fiebre, dolor abdominal y malestar)

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9
Q

Riesgos que ocasiona la Hepatitis B

A

cirrosis y hepatocarcinoma

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10
Q
A
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11
Q
A
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11
Q

Riesgo de infección crónica por Hepatitis B (porcentaje)

A

90% en transmisión vertical
30-50% infección a los 1-5años
5% en adultos
20% inmunodeficientes
40% px hemodialisis

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12
Q
A
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13
Q

Tratamiento para Hepatitis B

A

Vacuna recombinante con antígeno de superficie (si viene en esquema de vacunacion)- 4 dosis
Tratamiento contra la transcriptasa reversa

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14
Q

dx hepatitis B

A

serologia

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