virus Flashcards

1
Q

General Characteristics of Viruses

A

obligatory intracellular parasites (Cannot grow or replicate independent of a host cell)
-Contain DNA or RNA
* Contain a protein coat

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2
Q

Viruses (not alive)

A

-Acellular (not cell-based)
-Are assembled; do not grow
-Cannot replicate independently; obligate
intracellular parasites

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3
Q

Viruses (alive)

A

Are made of organic molecules (proteins; nucleic acid

Have the ability to take control of their host cell

They evolve over generations; ancestral lineage

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4
Q

Bacteriophages

A

viruses that infect bacteria-

Most viruses infect only specific types of cells
in one host
* Determined by specific host attachment sites and
cellular factors

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5
Q

Lytic replication

A

Viral replication usually results in death and lysis of the host
cell
– Five stages of lytic replication cycle
* Attachment
* Entry
* Synthesis
* Assembly
* Release

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6
Q

Lysogenic cycle

A

 Phage lies latent until triggered to enter lytic cyle
 Bacteria does not die until phage enters lytic cyle
 After attachment and entry of the genome, phage
integrates into host chromosome as a prophage
 Trigger causes phage to enter lytic cycle with
biosynthesis, assembly (maturation), and releas

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7
Q

Generalized transduction

A

Random bacterial
DNA is packaged inside a phage and transferred
to a recipient cell

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8
Q

Specialized transduction

A

: Specific bacterial
genes are packaged inside a phage and
transferred to a recipient cell

Some very common bacterial exotoxins are passed via
specialized transduction
* Shiga toxin
* Diphtheria toxin
* Cholera toxin
* Botulinum toxin
* Scarlet fever toxin

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