gamma Flashcards
Genus Pseudomonas
-Opportunistic pathogens; nosocomial infections
-Naturally resistant to many antimicrobial agents
-Metabolically diverse (can break down
hydrocarbons )
-in soil and moist environments
-Can infect animals and plants
Pseudomonas aeruginosa
Gram negative rod; encapsulated
* P. aeruginosa is inhabitant of water and soil
- Can grow in biofilms in sinks, showers, drains, soap dispensers,
– Can infect almost any organ or system once in body
* Can colonize the lungs of cystic fibrosis patients (forms
biofilm)
Opportunistic infections (grows under the surface of burns)
Pseudomonas Infection
Diagnosis,
treatment,
and
prevention
- Pyocyanin discoloration indicates massive infection
-Treatment is difficult because of natural multi-drug resistance
-, but infections typically
don’t occur in healthy individuals
– Exceptions:
» Ear infections (swimmer’s ear)
» Hot tub folliculitis
Legionella
Found in streams, warm-water pipes, and cooling
towers
- Causes legionellosis (a serious type of pneumonia
(lung infection)
INHALATION
In the natural environment, Legionella lives within
amoebae or other protozoa
upon inhalation, the bacteria can infect alveolar
macrophages, where the bacteria can replicate
Coxiella burnetii
(Order of Legionellae’s)
causes Q fever (cause flu-like
symptoms, or have life-threatening complications)
-zoonotic
-transmitted via aerosols or milk
-inhalation of a spore-like small-cell variant
-obligate intracellular pathogenic parasite
Bacterial Gastroenteritis
: Cholera
Vibrio cholerae
– Occurs in salt- and freshwater
-virulence factor is production of
cholera toxin
-abrupt onset of watery diarrhea
– Dehydration (hypotension, seizures, possibly death)
Vibrio vulnificus
causes necrotizing wound infections
that may occur in injured skin exposed to contaminated
marine water
Enterobacteriales
-Inhabit the intestinal tract;
ferment carbohydrates
-Facultative anaerobes
-resistant to beta-lactam antibiotics
Escherichia (E.COLI)
(Order Enterobacteriales)
indicator of fecal contamination; causes
foodborne disease and urinary tract infection
- easy to culture (grows in isolation)
- grows well in laboratory (robust)
- 20 minute generation time (in lab
Salmonella
(Order Enterobacteriales)
2400 serovars
Found in the intestines of reptiles (birds)
Common form of foodborne illness
Salmonella enterica serotype Typhi causes typhoid
fever
Typhoid disease spread by contaminated
food and water. Symptoms of typhoid include lasting
high fevers, weakness, stomach pains, headache, and
loss of appetite
Shigella
(Order Enterobacteriales)
Causes bacillary dysentery ( diarrhea containing blood or mucus)
-Shiga toxin causes destruction of red blood cells and
kidney problems (Hemolytic uremic syndrome (HUS)
K. pneumoniae
(Order Enterobacteriales)
causes pneumonia
Serratia
(Order Enterobacteriales)
Produces red pigment
Common cause of nosocomial infection (originating in a hospital.)
Proteus
(Order Enterobacteriales)
Swarming motility; colonies form concentric rings
Enterobacter
(Order Enterobacteriales)
E. cloacae and E. aerogenes cause urinary tract
infections and nosocomial infections