Virology Flashcards
What type of disease is transferred from animals to humans?
Zoonotic diseases
Capsid
protein coat surrounding virus genetic material
What do viruses lack?
Standard cellular organelles
Describe the virus reproduction cycle
-Viruses do not have the genetic capability to multiply for division so they hijack host machinery to create an assembly line of multiplication
What protein makes up the capsid?
Capsid is made up of capsomeres held together by non-covalent bonds
Nucleocapside=
capsid + Virus nucleic acid
Describe the viral envelope
Usually a lipid bilayer derived from host cellCovered in glycoproteins that resemble spikes
What are different shapes of viruses?
1) Filament2) Bullet3) Tadpole4) Rod5) Brick6) Spherical
Define pleomorphism
ability of some virus to alter their shape or size
6 Steps of viral replication
1) Attachment 2) Penetration 3) Uncoating 4) Synthesis of viral nucleic acid and protein 5) Assembly line and maturation 6) Release in Large numbers
Varying impacts of virus replication in host
1) Cell Death 2) No apparent change 3)Transformation of cell to malignant one 4) Fusion of cells (multinucleated)
What is the role of the ICTV?
sets up the different classifications of cells