Virology 2 Flashcards

1
Q

What is the presence of a virus in the blood called?
A) Viremia
B) Bacteremia
C) Fungemia
D) Septicemia

A

A

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2
Q

What is the final step in viral pathogenesis?
A) Viral spread
B) Cell injury
C) Viral shedding
D) Recovery

A

Answer: C) Viral shedding

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3
Q

Which factor does NOT influence the outcome of a viral infection?
A) Host
B) Environment
C) Agent
D) Virus color

A

Answer: D) Virus color

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4
Q

Which of the following is NOT a step in viral pathogenesis?
A) Entry and primary replication
B) Viral spread and cell tropism
C) Host mutation
D) Recovery from infection

A

Answer: C) Host mutation

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5
Q

What occurs during the cell injury stage?
A) Viruses remain dormant
B) The host shows clinical signs of illness
C) The virus spreads through the environment
D) The host becomes resistant to all infections

A

Answer: B) The host shows clinical signs of illness

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6
Q

Which of the following is a direct mode of transmission?
A) Airborne transmission
B) Vector-borne transmission
C) Skin-to-skin contact
D) Waterborne transmission

A

Answer: C) Skin-to-skin contact

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7
Q

What type of transmission occurs when a mosquito spreads a virus?
A) Airborne
B) Vehicle-borne
C) Direct contact
D) Vector-borne

A

D

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8
Q

What is an example of vehicle-borne transmission?
A) A person sneezing near another person
B) Consuming contaminated food
C) A mosquito bite
D) Direct skin contact

A

Answer: B) Consuming contaminated food

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9
Q

Which specimen is preferable for detecting rotavirus?
A) Blood
B) Stool
C) Urine
D) Serum

A

Answer: B) Stool

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10
Q

What is the first step in viral pathogenesis?
A) Viral shedding
B) Entry & Primary Replication
C) Cell injury & Clinical illness
D) Recovery from infection

A

B

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11
Q

Which virus family includes MERS-CoV, SARS-CoV, and COVID-19?
A) Adenoviruses
B) Coronaviruses
C) Herpesviruses
D) Enteroviruses

A

B

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12
Q

What is the most common route of systemic viral spread?
A) Nervous system
B) Lymphatics and bloodstream
C) Digestive tract
D) Direct skin contact

A

B

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13
Q

Which mode of transmission involves direct contact?
A) Airborne
B) Vector-borne
C) Droplet
D) Fomite transmission

A

Answer: C) Droplet

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14
Q

What is an example of indirect transmission?
A) Skin-to-skin contact
B) Kissing
C) Airborne spread
D) Sexual contact

A

Answer: C) Airborne spread

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15
Q

What type of specimen is preferred for detecting RSV and influenza?
A) Urine
B) Nasopharyngeal swab
C) Blood culture
D) Stool sample

A

Answer: B) Nasopharyngeal swab

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16
Q

What specimen is required for detecting CMV in urine?
A) 2 ml of urine
B) 5 ml of urine
C) At least 10 ml of urine
D) 1 ml of urine

A

Answer: C) At least 10 ml of urine

17
Q

What does a Tzanck smear detect?
A) Influenza virus
B) CMV
C) HSV or VZV
D) Enterovirus

19
Q

What is the primary virus detected in a blood culture?
A) Influenza
B) CMV
C) Rotavirus
D) Adenovirus

A

Answer: B) CMV - Cytomegalovirus

20
Q

Which virus can be detected in cerebrospinal fluid?
A) Enteroviruses
B) Mumps
C) Rubella
D) Rhinovirus

A

Answer: A) Enteroviruses

20
Q

Which virus is detected in bone marrow samples?
A) Herpes simplex
B) Parvovirus B19
C) Influenza
D) RSV

A

Answer: B) Parvovirus B19

21
Q

What type of specimen is best for antibody testing?
A) Throat swab
B) Serum
C) Nasopharyngeal aspirate
D) Stool sample

A

Answer: B) Serum

22
Q

Which medium is used for viral transport?
A) Buffered saline
B) VTM (Viral Transport Media)
C) Nutrient agar
D) MacConkey agar

23
Q

What temperature should viral specimens NOT be frozen at?
A) -20°C
B) 4°C
C) -80°C
D) Room temperature

A

Answer: A) -20°C

24
Q

What type of blood sample is best for viral isolation?
A) Whole blood
B) Serum
C) Plasma
D) Blood clot

A

Answer: A) Whole blood

25
Q

What is an essential component of VTM?
A) Bacterial culture medium
B) Protein stabilizers
C) Fungal inhibitors
D) All of the above

A

Answer: D) All of the above

27
Q

What is the best sample for detecting respiratory viruses?
A) Bronchoalveolar wash
B) Urine sample
C) Skin lesion swab
D) Stool sample

A

Answer: A) Bronchoalveolar wash

28
Q

What is the recommended condition for storing serum for antibody testing?
A) At room temperature
B) Refrigerated at 4°C
C) Frozen at -20°C
D) Both B and C

28
Q

Which virus is commonly detected in vesicular skin lesions?
A) Influenza virus
B) HSV or VZV
C) Enterovirus
D) Rotavirus

A

Answer: B) Herpes Simplex Virus (HSV) or VZV - Varicella Zoster Virus

29
Q

What should be done to specimens if processing is delayed?
A) Freeze at -20°C
B) Keep at room temperature
C) Refrigerate
D) Discard the sample

A

Answer: C) Refrigerate

30
Q

What type of virus is commonly found in stool samples?
A) Herpes simplex
B) Rotavirus
C) Influenza
D) COVID-19

A

Answer: B) Rotavirus

31
Q

What type of specimen is collected in a sterile tube with anticoagulant for viral detection?
A) Blood
B) Urine
C) Nasopharyngeal swab
D) Stool

32
Q

Which method is best for detecting viral infections in the lower respiratory tract?
A) Throat swab
B) Blood test
C) Bronchoalveolar lavage
D) Skin biopsy