Virology 2 Flashcards
Poliomyelitis
flaccid, asymmetrical paralysis, respiratory paralysis
Poliovirus
Genus: Enterovirus
Family: Picornaviridae
Prevention:
Salk (killed) - IM
Sabin (live attenuated) - oral
TYPE A
Herpangina, hand foot (weakness) and mouth disease (ulceration)
Coxsackie virus
Genus: Enterovirus
Family: Picornaviridae
TYPE B
Pleurodynia/ epidemic myalgia
myocarditis, pericarditis
Coxsackie virus
Genus: Enterovirus
Family: Picornaviridae
cytopathogenic virus that mainly affects the intestinal tract
entreic cytopathic human orphan virus (ECHO)
Genus: Enterovirus
Family: Picornaviridae
Colds from picornaviridae
Genus: Rhinovirus
Family: Picornaviridae
Hepatitis A
Genus: Hepatovirus
Family: Picornaviridae
Acute hepatitis
Fecal oral route
Eastern equine encephalitis virus
Horse
Alphavirus (arbovirus)
Togaviridae
Western equine encephalitis virus
Horse
Alphavirus (arbovirus)
Togaviridae
Venezuela equine encephalitis virus
Horse
Alphavirus (arbovirus)
Togaviridae
Chikungunya equine encephalitis virus
Horse and human
Alphavirus (arbovirus) - aedis aegypti
Togaviridae
German measles
aka 3-day measles/ rubella
generalized maculopopular rash
Rubella virus
Genus: Rubiviruses
Family: Togaviridae
Yellow fever virus
causes jaundice
Flaviviridae (mostly arboviruses)
Dengue/Breakbone fever
dengue virus
dengue hemorrghagic fever
4’oclock habit
Flaviviridae (mostly arboviruses- aedis aegypti)
Hepatitis C
Acute hepatitis
Fecal oral route
Tx: a-interferon, RIBAVIRIN
Flaviviridae (mostly arboviruses)
Hepatitis G
Blood transfusion
Flaviviridae (mostly arboviruses)
conjunctivitis via aedis aegypti
Zika virus
Flaviviridae (mostly arboviruses)
epidemic acute gastroenteritis
norwalk/norovirus
Calciviridae
Hepatitis E
Acute hepatitis
Fecal oral route
Calciviridae
SARS
severe acute respiratory syndrome
coronaviridae
- spikes (peplomers)
- crownlike
MERSCOV
middle east respiratory syndrome coronavirus
coronaviridae
- spikes (peplomers)
- crownlike
Human immunodeficiency virus
retroviridae (containse reverse transcriptase)
Dx:
elisa - enzyme linked immonoabsorbent assay (gold standard)
Western blot test - confirmatory
Southern blot test - nucleic acid hybridization
bullet shaped virus with spiked envelope
rhabdoviridae
histopathological findings: negribodies
Rabies virus
genus: Lyssavirus
Rhabdoviridae
short prodomal phase
acute neurologic phase
coma
stomatitis of horse and cattle
Vesiculovirus
Rhabdoviridae
sore or inflammation of inside the mouth
MARV
Marburg virus
Rousettus bat colonies in mines or caves
Filoviridae
severe hemorrhagic fever
ebola virus
origin: west africa (bats)
Filoviridae
Influenza
Influenza virus
Orthomyxoviridae
Birds:
hemagglutinnin (15)
neuraminidase (9)
Swine - H1,H3
Humans: (First - H5N1)
H1,H2,H3,H5
N1,N2
pneumonia in infants <6 mos.
Respiratory syncital virus (RSV)
Parainfluenzavrius
Paramyxoviridae
parotitis/ parotid salivary grand inflammation
Mumps Virus
Complications: orchitis (inflammation of testes)
Paramyxoviridae
Hard measles
Rubeola virus
kopliks spot
- coryza - inflamm. of nose mucosa
- cough
conjunctiva
oral lesions w/ bluish white center and red margin
Paramyxoviridae
Lassa fever
arenaviridae
bursh rats/mastomys rats
western africa
DOC: Ribavirin
most common cause of severe diarrhea in infants & children
stomach flu
rotavirus
reoviridae
results to premature labor and spontaneous abortion
measles
influenza for human and animals
massive epidemic and pandemic
TYPE A
influenza for humans
TYPE B
influenza for humans & swine
TYPE C
colorado tick fever
caused by coltivirus
Reoviridae
Sandfly fever
aka 3-day fever
influenza like
caused by phlebovirus
bunyaviridae
malignant tumor in mesodermal tissue
sarcoma
malignant tumor of lymphoid tissue
lymphoma
malignant tumor of epithelial cells
carcinoma
